CAS 132813-14-0

2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine

Description:

2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine is a chemical compound characterized by its complex bicyclic structure, which includes a cyclooctane ring fused with a pyridine moiety. The presence of a chlorine atom and a fluorophenyl group contributes to its unique reactivity and potential biological activity. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents, depending on the specific conditions. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways. The halogen substituents can influence the compound's lipophilicity and binding affinity to biological targets. Additionally, the stereochemistry of the hexahydrocycloocta[b]pyridine framework may play a crucial role in its pharmacological properties. As with many organic compounds, safety and handling precautions should be observed, given the presence of halogens, which can impart toxicity or environmental concerns.

Formula: C₁₇H₁₇ClFN

InChI: InChI=1/C17H17ClFN/c18-17-11-15(12-7-9-13(19)10-8-12)14-5-3-1-2-4-6-16(14)20-17/h7-11H,1-6H2

SMILES: C1CCCc2c(CC1)c(cc(Cl)n2)c1ccc(cc1)F

Synonyms:

• 2-chloro-4-(4-fluorophenyl)5,6,7,8,9,10-hexahydrocycloocta[b]pyridine
• Blonanserin Impurity 14
• Cycloocta[b]pyridine, 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-
• Blonanserin Intermediate
• 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocyclooctapyridine
• BlonserinImpurity14
• 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[...
• 2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10...
• 132813-14-0

Cycloocta[b]pyridine, 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-

CAS: 132813-14-0

Formula: C₁₇H₁₇ClFN

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.7750

Ref: IN-DA00117P

2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine

CAS: 132813-14-0

2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine

Purity: 98%

Molecular weight: 289.78g/mol

Ref: 54-PC1005539

Blonanserin Impurity 14

CAS: 132813-14-0

Formula: C₁₇H₁₇ClFN

Molecular weight: 289.78

Ref: 4Z-B-5619

2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine

CAS: 132813-14-0

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 289.7799987792969

Ref: 10-F214810

2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine

Controlled Product

CAS: 132813-14-0

Applications 2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine is an intermediate in the synthesis of Blonanserin (B595850), a 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.
References Oka, T., et al.: Life Sci., 76, 225 (2004), Singh, A., et al.: Int. Med. J., 12, 175 (2005), Ochi, T., et al.: Bioorg. Med. Chem., Lett., 15, 1055 (2005),

Formula: C₁₇H₁₇ClFN

Color and Shape: White To Off-White

Molecular weight: 289.775

Ref: TR-C374775

2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine

CAS: 132813-14-0

Formula: C₁₇H₁₇ClFN

Molecular weight: 289.78

Ref: ST-EA-CP-B79004