CAS 132866-11-6
:Lercanidipine hydrochloride
Description:
Lercanidipine hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension. It belongs to the dihydropyridine class of calcium antagonists, which work by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. The substance is characterized by its high lipophilicity, which enhances its absorption and bioavailability. Lercanidipine exhibits a long half-life, allowing for once-daily dosing, which improves patient compliance. It is typically administered in its hydrochloride salt form, which enhances its solubility in aqueous solutions. The compound is known for its selectivity for peripheral blood vessels, minimizing effects on cardiac contractility and heart rate. Common side effects may include peripheral edema, headache, and flushing. As with other calcium channel blockers, caution is advised in patients with certain cardiovascular conditions. Overall, lercanidipine hydrochloride is an effective antihypertensive agent with a favorable pharmacokinetic profile.
Formula:C36H42ClN3O6
InChI:InChI=1/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H
InChI key:InChIKey=WMFYOYKPJLRMJI-UHFFFAOYSA-N
SMILES:C(OC(CN(CCC(C1=CC=CC=C1)C2=CC=CC=C2)C)(C)C)(=O)C=3C(C(C(OC)=O)=C(C)NC3C)C4=CC(N(=O)=O)=CC=C4.Cl
Synonyms:- 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)Methylamino]-1,1-Dimethylethyl Methyl Ester Hydrochloride
- 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
- 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylicAcid2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimeth
- 1-[(3,3-Diphenylpropyl)(Methyl)Amino]-2-Methylpropan-2-Yl Methyl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate Hydrochloride (1:1)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester, monohydrochloride
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, hydrochloride (1:1)
- Cardiovasc
- Carmen
- Corifeo
- Lercadip
- Lercan
- Lercanidipine Hcl
- LercanidipineHcl
- Lercanidipinehydrochloride(Forr&Donly)
- Lercapin
- Lercaridipin HCL
- Lercaton
- Lerkamen
- Lervasc
- Lerzam
- Lotensyl
- Rec 15/2375
- Renovia
- Vasodip
- Zandip
- Zanicor
- Lercanidipine hydrochloride
- BCL-10 human
- B-cell lymphoma/leukemia 10
- 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)MethylaMino]-1,1-diMethylethyl] 5-Methyl ester,hydrochloride (1:1)
- Lercaridipine
- Lercanidipine hemihydrate hydrochloride
- B-cell CLL/lymphoma 10
- CLAP
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride
- CIPER
- 75
- O3-[1-[3,3-diphenylpropyl(methyl)amino]-2-methyl-propan-2-yl] O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
- 3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
- c-E10
- CARD-containing molecule enhancing NF-κ-B
- Lercanidipine hydrochloride heMihydrate
- 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-[2-[3,3-diphenylpropyl(methyl)amino]-1,1-dimethyl-ethyl] ester O5-methyl ester hydrochloride
- mE10
- See more synonyms
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Found 15 products.
Lercanidipine Hydrochloride
CAS:Formula:C36H41N3O6·HClPurity:>98.0%(T)(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:648.203,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, hydrochloride (1:1)
CAS:Formula:C36H42ClN3O6Purity:98%Color and Shape:SolidMolecular weight:648.1882Lercanidipine HCl
CAS:Formula:C36H41N3O6·HClColor and Shape:Yellow SolidMolecular weight:611.74 36.46Lercanidipine-13C-d3 HCl
CAS:Formula:C3513CH38D3N3O6·HClColor and Shape:Yellow SolidMolecular weight:615.75 36.46Lercanidipine hydrochloride
CAS:Formula:C36H41N3O6·HCl·xH2OPurity:(HPLC) ≥ 98.0%Color and Shape:Light-yellow to yellow powder or crystalsMolecular weight:648.19 (anhydrous)Lercanidipine hydrochloride
CAS:<p>Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.</p>Formula:C36H41N3O6·HClPurity:99.86% - 99.91%Color and Shape:Pale-Yellow PowderMolecular weight:648.19Lercanidipine Hydrochloride
CAS:Controlled ProductFormula:C36H41N3O6·ClHColor and Shape:Light YellowMolecular weight:648.19Lercanidipine HCl - Bio-X ™
CAS:<p>Lercanidipine is a calcium channel blocker that is used for the treatment of hypertension. This drug inhibits ion channels and interferes with the release of calcium from the sarcoplasmic reticulum. As a result, coronary and systemic arteries are dilated, allowing for an increased supply of oxygen to myocardial tissue. .</p>Formula:C36H41N3O6•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:648.19 g/molLercanidipine hydrochloride
CAS:<p>Calcium channel blocker</p>Formula:C36H42ClN3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:648.19 g/mol3-(1-((3,3-Diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
CAS:Purity:98%Molecular weight:648.2000122
