CAS 13292-46-1: rifampicin

Description:Rifampicin, with the CAS number 13292-46-1, is a semi-synthetic antibiotic belonging to the rifamycin class. It is primarily used to treat bacterial infections, particularly tuberculosis and leprosy, by inhibiting bacterial RNA synthesis. The compound exhibits a reddish-orange color and is known for its lipophilic nature, allowing it to penetrate cell membranes effectively. Rifampicin has a relatively low solubility in water but is soluble in organic solvents such as ethanol and acetone. Its mechanism of action involves binding to the beta-subunit of bacterial RNA polymerase, thereby preventing the transcription of DNA into RNA. This antibiotic is often administered in combination with other drugs to prevent the development of resistance. Additionally, rifampicin is metabolized in the liver and can induce cytochrome P450 enzymes, affecting the metabolism of other medications. Due to its potent effects and potential side effects, including hepatotoxicity and interactions with other drugs, careful monitoring is essential during treatment.

Formula:C₄₃H₅₈N₄O₁₂

InChI:InChI=1/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20?/t21?,23-,24-,25-,29+,34+,35-,39+,43+/m1/s1

InChI key:InChIKey=JQXXHWHPUNPDRT-ZNQWNCHJSA-N

SMILES:O=C(OC1C(C)C(OC)C=COC2(OC3=C(C2=O)C4=C(O)C(C=NN5CCN(C)CC5)=C(NC(=O)C(=CC=CC(C)C(O)C(C)C(O)C1C)C)C(O)=C4C(O)=C3C)C)C

Synonyms:
(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv.
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-, 21-acetate
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-, 21-acetate
3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin
3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV
5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)-naphtho[2,1-b]furan-1,11(2H)-dione 21-acetate
Abrifam
Ba 41166/E
Dipicin
See more synonyms
Eremfat
Famcin
L 5103 Lepetit
Nih 10782
Nsc 113926
R-Cin
R/Amp
RIF
Refampicin
Rifa
Rifacap
Rifactine
Rifadin
Rifadin I.V.
Rifadine
Rifaldazine
Rifaldin
Rifamate
Rifamicin AMP
Rifampicin SV
Rifampicina
Rifampicine
Rifampin
Rifamycin AMP
Rifamycin SV Sodium
Rifamycin, 3-[[(4-methyl-1-piperazinyl)imino]methyl]-
Rifamyzin 3-(4-Methyl-Piperazinyl)Iminomethyl
Rifandin
Rifaprodin
Rifater
Rifobac
Rifodex
Rifoldin
Rifoldine
Riforal
Rimactan
Rimactane
Rimapen
Rimycin
Sinerdol
Tubocin

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Product data	Purity	Price range	Estimated delivery
Rifampicin REF: 3D-AR11351CAS: 13292-46-1	Min. 95%	110.00 €~2,181.00 €	Tue 20 May 25
Rifampicin (RFP) (Rifampin) for cell culture, 97-102%, Endotoxin (BET) 0.05EU/mg REF: SR-46143CAS: 13292-46-1	97-102%	75.00 €~253.00 €	Tue 10 Jun 25
Rifampicin (RFP) (Rifampin), 97-102% REF: SR-12310CAS: 13292-46-1	97-102%	27.00 €~37.00 €	Tue 10 Jun 25
Rifampicin, Antibiotic for Culture Media Use Only REF: 3D-R-6000CAS: 13292-46-1	Min. 90.0 Area-%	To inquire	Fri 20 Jun 25