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CAS 13292-47-2

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3-[[[2,6-Dimethyl-4-(phenylmethyl)-1-piperazinyl]imino]methyl]rifamycin

Description:
3-[[[2,6-Dimethyl-4-(phenylmethyl)-1-piperazinyl]imino]methyl]rifamycin, identified by its CAS number 13292-47-2, is a synthetic derivative of rifamycin, a class of antibiotics known for their efficacy against bacterial infections, particularly tuberculosis. This compound features a complex structure that includes a rifamycin core, which is characterized by a naphthalenic ring system and a characteristic rifamycin chromophore. The presence of the piperazine moiety enhances its pharmacological properties, potentially improving its ability to penetrate bacterial cell walls. The dimethyl and phenylmethyl substituents contribute to its lipophilicity, which may influence its absorption and distribution in biological systems. As a member of the rifamycin family, it is expected to exhibit antibacterial activity by inhibiting bacterial RNA synthesis through binding to DNA-dependent RNA polymerase. However, specific pharmacokinetic and pharmacodynamic properties, as well as potential side effects, would require further investigation through clinical studies. Overall, this compound represents a significant area of interest in the development of new antimicrobial agents.
Formula:C51H66N4O12
Synonyms:
  • Rifamycin, 3-[[[2,6-dimethyl-4-(phenylmethyl)-1-piperazinyl]imino]methyl]-
  • 3-[[[2,6-Dimethyl-4-(phenylmethyl)-1-piperazinyl]imino]methyl]rifamycin
  • 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 8-[N-(4-benzyl-2,6-dimethyl-1-piperazinyl)formimidoyl]-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate
  • 2′,6′-Dimethyl-N4′-benzyl-N4′-demethyl rifampicin
  • 2,6-Dimethyl-4-N-benzyldemethylrifampicin
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