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CAS 133-15-3

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Calcium p-aminosalicylate

Description:
Calcium p-aminosalicylate is a chemical compound that serves primarily as an anti-tuberculosis agent. It is a calcium salt of p-aminosalicylic acid, which is known for its role in the treatment of tuberculosis, particularly in cases where resistance to other medications occurs. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water, making it suitable for various pharmaceutical formulations. Its mechanism of action involves inhibiting the synthesis of folic acid in bacteria, thereby impeding their growth and replication. In addition to its therapeutic uses, calcium p-aminosalicylate may exhibit mild side effects, including gastrointestinal disturbances and hypersensitivity reactions. It is important to handle this compound with care, following appropriate safety guidelines, as with any pharmaceutical agent. Overall, calcium p-aminosalicylate is a valuable component in the arsenal against tuberculosis, particularly in multidrug-resistant cases, and is utilized in conjunction with other anti-tuberculosis medications to enhance treatment efficacy.
Formula:C7H7NO3Ca
InChI:InChI=1S/C7H7NO3.Ca/c8-4-1-2-5(7(10)11)6(9)3-4;/h1-3,9H,8H2,(H,10,11);
InChI key:InChIKey=RPGYNYKTZJZLNN-UHFFFAOYSA-N
SMILES:C(O)(=O)C1=C(O)C=C(N)C=C1.[Ca]
Synonyms:
  • 4-Amino-2-Hydroxy-Benzoic Acid
  • 4-Aminosalicylic acid calcium salt
  • Aminacyl
  • Aminosalicylate calcium
  • Benzoic acid, 4-amino-2-hydroxy-, calcium salt (2:1)
  • Ca-PAS
  • Calcipas
  • Calcium 4-aminosalicylate
  • Calcium Bis(4-Amino-2-Hydroxybenzoate)
  • Calcium aminosalicylate
  • See more synonyms
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