CAS 133029-32-0

Polihexanide HCl

Description:

Polihexanide HCl, also known as polyhexamethylene biguanide hydrochloride (PHMB), is a synthetic polymer with antimicrobial properties, commonly used in various applications, including disinfection and wound care. It is characterized by its broad-spectrum activity against bacteria, fungi, and some viruses, making it effective in preventing infections. The substance is soluble in water, allowing for easy formulation in aqueous solutions. Polihexanide exhibits low toxicity and is generally well-tolerated in medical and cosmetic applications, which contributes to its popularity in products like antiseptic solutions, contact lens solutions, and personal care items. Its mechanism of action involves disrupting microbial cell membranes, leading to cell lysis. Additionally, PHMB is known for its residual antimicrobial activity, providing prolonged protection after application. Due to its biocompatibility, it is often used in wound dressings and surgical procedures. However, like any chemical agent, its use should be monitored to prevent potential resistance development and ensure safety in various applications.

Formula: C₅H₁₄N₆

InChI: InChI=1/C18H40N10.ClH/c1-15(19)24-11-7-3-4-9-13-26-17(21)28-18(22)27-14-10-6-5-8-12-25-16(20)23-2;/h3-14H2,1-2H3,(H2,19,24)(H3,20,23,25)(H5,21,22,26,27,28);1H

InChI key: InChIKey=XKFDVLUHBRJZQF-UHFFFAOYSA-N

SMILES: N(C(NC(=N)N)=N)CCCN

Synonyms:

• Acticide PHB 20
• Hexan-1-Ide
• Imidodicarbonimidic diamide, N-(3-aminopropyl)-, homopolymer
• Pg 2198
• Phmb
• Poly(hexamethylenebiguanide)hydrochloride
• Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride
• Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride Polyaminopropyl biguanide
• Polyamine-propyl-biguanidine
• Polyaminopropyl biguanide
• Polyhexamethylene Biguanide HCl
• Polyhexamethylene Biguanide Hydrchloride
• Polyhexamethylene biguanide Hydrochloride
• POLYAMINE PROPYL BIGUANIDE
• N-(3-Aminopropyl)imidodicarbonimidic diamide homopolymer

Polyaminopropyl biguanide

CAS: 133029-32-0

Polyaminopropyl biguanide

Purity: 99%

Ref: 54-OR1014754

Polyaminopropyl biguanide

CAS: 133029-32-0

Polyaminopropyl biguanide is a disinfectant that belongs to the group of polymyxins. It is a broad-spectrum antimicrobial agent that inhibits the growth of both Gram-positive and Gram-negative bacteria, including microorganisms resistant to other antibiotics. Polyaminopropyl biguanide has been shown to be effective against amoebae, such as Entamoeba histolytica, by penetrating the cytoplasmic membrane and disrupting protein synthesis. This product is also active against chitinase-producing organisms and can be used in disinfecting solutions.

Purity: Min. 95%

Color and Shape: Powder

Ref: 3D-FP173466