CAS 133052-90-1

3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

Description:

The chemical substance known as 3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione, with the CAS number 133052-90-1, is a complex organic compound characterized by its multi-ring structure, which includes indole and pyrrole moieties. This compound features a dimethylamino group, contributing to its potential biological activity and solubility properties. It is often studied for its pharmacological properties, particularly in the context of medicinal chemistry, where such structures may exhibit significant interactions with biological targets. The presence of multiple aromatic rings suggests potential for π-π stacking interactions, which can influence its behavior in biological systems. Additionally, the compound's functional groups may participate in hydrogen bonding, affecting its reactivity and stability. Overall, this substance is of interest in research related to drug development and may have implications in various therapeutic areas, although specific applications would depend on further empirical studies and evaluations.

Formula: C₂₅H₂₄N₄O₂

InChI: InChI=1S/C25H24N4O2/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31)

InChI key: InChIKey=QMGUOJYZJKLOLH-UHFFFAOYSA-N

SMILES: O=C1C(=C(C(=O)N1)C=2C=3C(NC2)=CC=CC3)C=4C=5C(N(CCCN(C)C)C4)=CC=CC5

Synonyms:

• 1H-Pyrrole-2,5-dione, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-
• 2-(1-(3-Dimethylaminopropyl)-indol-3-yl)-3-(indol-3-yl)maleimide
• 3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrol-2,5-dione
• 3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
• 3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione hydrochloride
• Bim 1
• Bis(indolyl)maleimide 1
• Bisindolylmaleimide I
• BisindolylmaleimideGF 109203X
• Gf 109203
• Gf-109203X

Bisindolylmaleimide 1

CAS: 133052-90-1

Very potent and selective inhibitor of protein kinase C

Formula: C₂₅H₂₄N₄O₂

Color and Shape: Red, Powder or crystals or crystalline powder

Molecular weight: 412.49

Ref: 02-J63401

1H-Pyrrole-2,5-dione, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-

CAS: 133052-90-1

Formula: C₂₅H₂₄N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 412.4837

Ref: IN-DA0011LB

Bisindolylmaleimide I

CAS: 133052-90-1

Bisindolylmaleimide I

Purity: ≥98%

Molecular weight: 412.48g/mol

Ref: 54-BUP10725

Bisindolylmaleimide I

CAS: 133052-90-1

Bisindolylmaleimide I

Formula: C₂₅H₂₄N₄O₂

Purity: By hplc: >99% (Typical Value in Batch COA)

Color and Shape: orange crystalline solid or powder

Molecular weight: 412.48g/mol

Ref: 54-BIMI0417

Bisindolylmaleimide I

CAS: 133052-90-1

Formula: C₂₅H₂₄N₄O₂

Purity: >97.0%(HPLC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 412.49

Ref: 3B-B5781

Bisindolylmaleimide I

CAS: 133052-90-1

Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.

Formula: C₂₅H₂₄N₄O₂

Purity: 98.19% - 98.75%

Color and Shape: Orange Solid

Molecular weight: 412.48

Ref: TM-T6513

Bisindolylmaleimide I base

CAS: 133052-90-1

Formula: C₂₅H₂₄N₄O₂

Molecular weight: 412.5

Ref: 7W-GL2668

GF 109203X

CAS: 133052-90-1

Stability Light Sensitive
Applications GF 109203X is a highly selective protein kinase C (PKC) inhibitor.
References Toullec, D., et. al.: J. Biol. Chem., 266, 1577 (1991)

Formula: C₂₅H₂₄N₄O₂

Color and Shape: Red Solid

Molecular weight: 412.48

Ref: TR-G368850

Bisindolylmaleimide I

CAS: 133052-90-1

Purity: 98%

Molecular weight: 412.19

Ref: 10-F861747

GF 109203X-D6

Controlled Product

CAS: 133052-90-1

Formula: C₂₅D₆H₁₈N₄O₂

Color and Shape: Neat

Molecular weight: 418.521

Ref: TR-G368852