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CAS 133054-21-4

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Fmoc-Thz-OH

Description:
Fmoc-Thz-OH, or 9-fluorenylmethoxycarbonyl-thiazolidine-4-carboxylic acid, is a chemical compound commonly used in peptide synthesis and drug development. It features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized to protect amino groups during the synthesis of peptides. The thiazolidine ring in its structure contributes to its unique properties, including potential biological activity. Fmoc-Thz-OH is typically a white to off-white solid, and its solubility can vary depending on the solvent, often being soluble in organic solvents like dimethyl sulfoxide (DMSO) and methanol. The compound is sensitive to moisture and should be stored in a dry environment to maintain its stability. Its applications extend beyond peptide synthesis, as it may also serve as a building block in the development of pharmaceuticals and biologically active compounds. As with many chemical substances, proper handling and safety precautions are essential when working with Fmoc-Thz-OH to avoid any potential hazards.
Formula:C19H17NO4S
InChI:InChI=1/C19H17NO4S/c21-18(22)17-10-25-11-20(17)19(23)24-9-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H,21,22)/t17-/m0/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=O)N1CSC[C@H]1C(=O)O
Synonyms:
  • Fmoc-D-Thiaproline
  • Fmoc-D-Thiazolidine-4-Carboxylic Acid
  • Fmoc-D-Thioproline
  • Fmoc-(S)-Thiazolidine-4-Carboxylic Acid
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-Thiazolidine-D-4-Carboxylic Acid
  • (S)-N-(9-Fluoroenylmethyloxycarbonyl)-Thiazolidine-4-Carboxylic Acid
  • NALPHA-9-Fluorenylmethoxycarbonyl-L-hepalidine
  • (4R)-3-[(9H-fluoren-9-ylmethoxy)carbonyl]-1,3-thiazolidine-4-carboxylic acid
  • Fmoc-D-Thz-Oh
  • (R)-3,4-Thiazolidinedicarboxylic acid 3-(9H-fluoren-9-ylmethyl) ester
  • See more synonyms
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