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CAS 133066-61-2

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PACLITAXEL SIDE CHAIN NO 1

Description:
Paclitaxel Side Chain No. 1, with the CAS number 133066-61-2, is a chemical compound that serves as a structural component of the anticancer drug paclitaxel, which is derived from the bark of the Pacific yew tree. This compound is characterized by its complex molecular structure, which includes a taxane core and specific side chains that contribute to its biological activity. The side chain plays a crucial role in the drug's mechanism of action, which involves the stabilization of microtubules and inhibition of cell division, making it effective against various types of cancer. The compound is typically a white to off-white solid and is soluble in organic solvents. Its synthesis and characterization are important for the development of paclitaxel analogs and derivatives aimed at improving therapeutic efficacy and reducing side effects. As a key intermediate in the synthesis of paclitaxel, it is of significant interest in pharmaceutical research and development.
Formula:C20H21NO4
Synonyms:
  • (3R,4S)-1-Benzoyl-3-[(Triethylsily)Oxy]-4-Phenyl-2-Azetidinone
  • (3R,4S)-1-Benzoyl-3-(2-Ethoxyethoxy)-4-Phenyl-2-Azetidione
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