CAS 1330782-76-7

TAK-931

Description:

TAK-931, with the CAS number 1330782-76-7, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is classified as a selective inhibitor of certain kinases, which are enzymes that play crucial roles in various cellular processes, including cell growth and division. The compound is characterized by its ability to modulate signaling pathways, making it a candidate for the treatment of specific types of cancer and other diseases where these pathways are dysregulated. TAK-931 exhibits a unique chemical structure that contributes to its selectivity and potency. Additionally, it has undergone various preclinical studies to evaluate its efficacy and safety profile. As with many investigational drugs, ongoing research is essential to fully understand its pharmacokinetics, mechanism of action, and potential side effects. Overall, TAK-931 represents a promising avenue in targeted therapy, reflecting the ongoing efforts to develop more effective and less toxic treatment options in oncology.

Formula: C₁₇H₁₉N₅OS

Synonyms:

• Simurosertib (TAK-931)
• 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1~{H}-pyrazol-4-yl)-3~{H}-thieno[3,2-d]pyrimidin-4-one
• SIMUROSERTIB
• (S)-6-(3-methyl-1H-pyrazol-4-yl)-2-(quinuclidin-2-yl)thieno[3,2-d]pyrimidin-4(3H)-one
• Thieno[3,2-d]pyrimidin-4(3H)-one, 2-(2S)-1-azabicyclo[2.2.2]oct-2-yl-6-(3-methyl-1H-pyrazol-4-yl)-
• TAK-931

Simurosertib

CAS: 1330782-76-7

Simurosertib (TAK-931) is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: <0.3 nM).

Formula: C₁₇H₁₉N₅OS

Purity: 99.93% - 99.93%

Color and Shape: Solid

Molecular weight: 341.43

Ref: TM-T12642L

Simurosertib

CAS: 1330782-76-7

Formula: C₁₇H₁₉N₅OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 341.4307

Ref: IN-DA01FN8X

Simurosertib

CAS: 1330782-76-7

Simurosertib

Purity: ≥98%

Molecular weight: 341.43g/mol

Ref: 54-BUP12698

Simurosertib

CAS: 1330782-76-7

Simurosertib is a molecule inhibitor that inhibits the synthesis of RNA and DNA. It binds to the enzyme polymerase II, which is required for replication of DNA. Simurosertib has been shown to have antitumour activity in vitro and in vivo. It is well-tolerated with an effective dose of 100 mg/kg, which is low relative to other chemotherapy drugs. The drug has potential as an antineoplastic agent against metastatic pancreatic cancer, colorectal cancer, and other cancers that are resistant to current therapies.

Formula: C₁₇H₁₉N₅OS

Purity: Min. 95%

Molecular weight: 341.4 g/mol

Ref: 3D-FDC78276