CAS 133081-24-0

6-Hydrazinonicotinic Acid

Description:

6-Hydrazinonicotinic acid is a chemical compound characterized by its hydrazine and pyridine functionalities. It features a hydrazine group (-NH-NH2) attached to the 6-position of a nicotinic acid structure, which is a derivative of pyridine. This compound is typically a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to its hydrophilic nature. It exhibits properties that make it useful in various applications, including as a potential ligand in coordination chemistry and in the synthesis of pharmaceuticals. The presence of both the hydrazine and carboxylic acid groups allows for diverse reactivity, including the formation of hydrazones and potential applications in drug development. Additionally, 6-hydrazinonicotinic acid may exhibit biological activity, making it of interest in medicinal chemistry. As with many chemical substances, handling should be done with care, considering safety data and potential hazards associated with hydrazine derivatives.

Formula: C₆H₇N₃O₂

InChI: InChI=1/C6H7N3O2/c7-9-5-2-1-4(3-8-5)6(10)11/h1-3H,7H2,(H,8,9)(H,10,11)

SMILES: c1cc(ncc1C(=O)O)NN

Synonyms:

• Hydralink 6-Hna Reagent
• Hydralink(Tm) 6-Hna Reagent
• 6-Hydrazinicotinic Acid
• 3-Pyridinecarboxylicacid,6-Hydrazino-
• 6-Hydrazino-Nicotinic Acid
• 6-Hydrazinopyridine-3-Carboxylic Acid
• 6-Hydrazinylnicotinic Acid
• 6-Hydrazinylpyridine-3-Carboxylic Acid

3-Pyridinecarboxylic acid, 6-hydrazinyl-

CAS: 133081-24-0

Formula: C₆H₇N₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 153.1387

Ref: IN-DA001480

6-Hydrazinylnicotinic acid

CAS: 133081-24-0

6-Hydrazinylnicotinic acid

Purity: 97%

Molecular weight: 153.141g/mol

Ref: 54-OR75080

6-Hydrazinonicotinic acid

CAS: 133081-24-0

Formula: C₆H₇N₃O₂

Purity: 95.0%

Color and Shape: Powder

Molecular weight: 153.141

Ref: 10-F065931

6-Hydrazino-3-pyridinecarboxylic acid

CAS: 133081-24-0

6-Hydrazino-3-pyridinecarboxylic acid is a potent inhibitor of angiogenesis. It inhibits the activity of vascular endothelial growth factor, which is a potent pro-angiogenic factor. 6HPCA has been shown to inhibit the growth of prostate cancer cells in vitro and tumor growth in vivo. The mechanism for this inhibition may be due to its ability to decrease levels of all-trans retinoic acid (RA), a potent pro-angiogenic molecule. 6HPCA also inhibits the proliferation of human serum, monoclonal antibody, and polymer drug uptake in cell culture systems. In addition, 6HPCA has low toxicity and low pharmacokinetic properties that have been demonstrated by several studies using radiolabeled analogues and autoradiography.

Formula: C₆H₇N₃O₂

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 153.14 g/mol

Ref: 3D-FH57311

6-Hydrazinonicotinic acid

Controlled Product

CAS: 133081-24-0

Applications 6-Hydrazinonicotinic acid

Formula: C₆H₇N₃O₂

Color and Shape: Neat

Molecular weight: 153.14

Ref: TR-H716503