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CAS 133083-36-0

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Fmoc-D-Lys(Boc)-OPfp

Description:
Fmoc-D-Lys(Boc)-OPfp is a chemical compound commonly used in peptide synthesis and research. It is a derivative of lysine, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group on the amino group and a tert-butyloxycarbonyl (Boc) protecting group on the side chain amino group. The presence of the OPfp (pentafluorophenyl) group indicates that it is an active ester, which enhances its reactivity in coupling reactions. This compound is typically utilized in solid-phase peptide synthesis, allowing for the selective protection and deprotection of functional groups during the assembly of peptides. Its structure contributes to the stability and solubility of intermediates, facilitating the synthesis of complex peptides. Additionally, the use of Fmoc and Boc protecting groups allows for mild deprotection conditions, making it suitable for sensitive amino acids. Overall, Fmoc-D-Lys(Boc)-OPfp is valued in the field of organic chemistry and biochemistry for its utility in synthesizing peptides with specific sequences and modifications.
Formula:C32H31F5N2O6
InChI:InChI=1/C32H31F5N2O6/c1-32(2,3)45-30(41)38-15-9-8-14-22(29(40)44-28-26(36)24(34)23(33)25(35)27(28)37)39-31(42)43-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,38,41)(H,39,42)/t22-/m1/s1
SMILES:CC(C)(C)OC(=NCCCC[C@H](C(=O)Oc1c(c(c(c(c1F)F)F)F)F)N=C(O)OCC1c2ccccc2c2ccccc12)O
Synonyms:
  • N'-(Tert-Butoxycarbonyl)-N-(9-Fluorenylmethyloxycarbonyl)-D-Lysine Pentafluorophenyl Ester
  • FMOC-N-EPSILON-BOC-D-LYSINE PENTAFLUOROPHENYL ESTER
  • (2,3,4,5,6-pentafluorophenyl)(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate
  • N6-Boc-N2-Fmoc-D-Lysine pentafluorophenyl ester
  • 2,3,4,5,6-pentafluorophenyl (2R)-6-{[(tert-butoxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoate
  • Perfluorophenyl N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-D-lysinate
  • FMOC-D-LYSINE(BOC)-OPFP
  • N-alpha-FMoc-N-epsilon-Boc-D-lysine pentafluorophenyl ester
  • FMOC-D-LYS(BOC)-OPFP
  • (R)-perfluorophenyl 1-(9H-fluoren-9-yl)-13,13-dimethyl-3,11-dioxo-2,12-dioxa-4,10-diazatetradecane-5-carboxylate
  • See more synonyms
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Purity (%)
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100
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0
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50
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90
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95
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100
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