CAS 133099-04-4

Darifenacin

Description:

Darifenacin is a medication primarily used to treat overactive bladder symptoms, such as urinary urgency, frequency, and incontinence. It belongs to the class of drugs known as antimuscarinics, which work by selectively inhibiting the M3 muscarinic acetylcholine receptors in the bladder, thereby reducing involuntary contractions. The chemical formula of darifenacin is C23H30N2O2, and it has a molecular weight of approximately 366.50 g/mol. This compound is characterized by its lipophilic nature, which contributes to its ability to penetrate biological membranes effectively. Darifenacin is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include dry mouth, constipation, and blurred vision, which are typical of anticholinergic medications. Its selectivity for the M3 receptor over other muscarinic receptors helps minimize systemic side effects, making it a preferred option for managing overactive bladder symptoms.

Formula: C₂₈H₃₀N₂O₂

InChI: InChI=1S/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,13-18,20H2,(H2,29,31)/t25-/m1/s1

InChI key: InChIKey=HXGBXQDTNZMWGS-RUZDIDTESA-N

SMILES: C(C(N)=O)([C@H]1CN(CCC=2C=C3C(=CC2)OCC3)CC1)(C4=CC=CC=C4)C5=CC=CC=C5

Synonyms:

• (3S)-(1-Carbamoyl-1,1-diphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]pyrrolidine
• (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
• (3S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-1-pyrrolidine
• (S)-(-)-3-(1-Carbamoyl-1,1-diphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]pyrrolidine
• (S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
• (S)-2-[1-[2-(2,3-Dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenylacetamide
• 2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide
• 2-{1-[2-(2,3-Dihydro-1-Benzofuran-5-Yl)Ethyl]Pyrrolidin-3-Yl}-2,2-Diphenylacetamide
• 3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-, (3S)-
• 3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-, (S)-
• Darifenacin intermediate
• Uk 88525
• Vesigard

Darifenacin

CAS: 133099-04-4

Darifenacin

Purity: ≥98%

Molecular weight: 426.55g/mol

Ref: 54-BUP01352

Darifenacin

CAS: 133099-04-4

Formula: C₂₈H₃₀N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 426.56

Ref: 4Z-D-171

Darifenacin

CAS: 133099-04-4

Darifenacin (UK-88525) is a muscarinic receptor M3 antagonist with anticonvulsant activity and can be used to study urinary incontinence and overactive bladder.

Formula: C₂₈H₃₀N₂O₂

Purity: 99.78%

Color and Shape: Solid

Molecular weight: 426.55

Ref: TM-T62320

Darifenacin

Controlled Product

CAS: 133099-04-4

Formula: C₂₈H₃₀N₂O₂

Color and Shape: Neat

Molecular weight: 426.55

Ref: TR-D070500