CAS 133099-07-7: Darifenacin hydrobromide
Description:Darifenacin hydrobromide is a medication primarily used to treat overactive bladder symptoms, such as urgency, frequency, and incontinence. It functions as a selective antagonist of the muscarinic acetylcholine receptors, particularly the M3 subtype, which are involved in bladder contraction. This selectivity helps minimize side effects commonly associated with anticholinergic drugs. The substance appears as a white to off-white crystalline powder and is soluble in water and methanol, which facilitates its formulation in various dosage forms. Darifenacin hydrobromide is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Common side effects may include dry mouth, constipation, and blurred vision, reflecting its anticholinergic activity. As with any medication, it is essential to consider contraindications and potential interactions with other drugs. Overall, darifenacin hydrobromide represents a targeted approach to managing bladder dysfunction, improving the quality of life for individuals affected by this condition.
Formula:C28H30N2O2·BrH
InChI:InChI=1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1
InChI key:InChIKey=UQAVIASOPREUIT-VQIWEWKSSA-N
SMILES:Br.O=C(N)C(C=1C=CC=CC1)(C=2C=CC=CC2)C3CN(CCC4=CC=C5OCCC5=C4)CC3
- Synonyms:
- (S)-3-(Carbamoyldiphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]pyrrolidine hydrobromide
- 2-[(3S)-1-[2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide hydrobromide
- 2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide hydrobromide (1:1)
- 2-{1-[2-(2,3-Dihydro-1-Benzofuran-5-Yl)Ethyl]Pyrrolidin-3-Yl}-2,2-Diphenylacetamide Hydrobromide (1:1)
- 3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-, hydrobromide (1:1), (3S)-
- 3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-, monohydrobromide, (3S)-
- 3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-, monohydrobromide, (S)-
- Darifenacin HBr
- Darilong
- Emselex
- See more synonyms
- Enablex
- UK 88525-04 hydrobromide
- Uk 88525-04
- {1-[2-(2,3-Dihydrobenzofuran-5-Yl)Ethyl]-3-Pyrrolidnyl}-2,2-Diphenylacetamide Hydrobromide
- Darifenacin hydrobromide