CAS 133107-64-9

INSULIN LISPRO (5.97 MG)

Description:

Insulin lispro is a rapid-acting insulin analog used primarily in the management of diabetes mellitus. It is designed to mimic the natural insulin response to meals, allowing for better glycemic control. The chemical structure of insulin lispro differs from that of human insulin by the substitution of the proline and lysine amino acids at the B28 and B29 positions, respectively. This modification results in a faster onset of action and a shorter duration of effect compared to regular human insulin. Insulin lispro is typically administered via subcutaneous injection and is often used in conjunction with long-acting insulins or other antidiabetic medications. Its pharmacokinetics are characterized by rapid absorption and a peak effect occurring within a short time frame after administration, making it particularly effective for controlling postprandial blood glucose levels. The CAS number 133107-64-9 uniquely identifies this compound, facilitating its recognition in scientific literature and regulatory contexts. As with all insulin therapies, careful monitoring of blood glucose levels is essential to avoid hypoglycemia and ensure optimal therapeutic outcomes.

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

InChI: InChI=1/C158H234N40O42S2.C99H155N25O35S4/c1-79(2)57-104(181-131(213)86(15)173-136(218)102(50-53-125(211)212)179-152(234)127(84(11)12)194-148(230)107(60-82(7)8)184-145(227)113(67-95-70-166-78-172-95)189-150(232)115(74-199)176-123(208)73-170-134(216)116(75-241)191-140(222)105(58-80(3)4)182-144(226)112(66-94-69-165-77-171-94)188-138(220)101(48-51-119(161)204)178-146(228)114(68-120(162)205)190-153(235)126(83(9)10)193-132(214)98(160)61-89-31-21-18-22-32-89)139(221)185-110(64-92-40-44-96(202)45-41-92)142(224)183-106(59-81(5)6)147(229)195-128(85(13)14)154(236)192-117(76-242)135(217)169-71-121(206)174-100(49-52-124(209)210)137(219)177-99(38-29-55-167-158(163)164)133(215)168-72-122(207)175-108(62-90-33-23-19-24-34-90)141(223)186-109(63-91-35-25-20-26-36-91)143(225)187-111(65-93-42-46-97(203)47-43-93)149(231)196-129(87(16)200)155(237)180-103(37-27-28-54-159)156(238)198-56-30-39-118(198)151(233)197-130(88(17)201)157(239)240;1-12-46(9)77(121-73(134)36-100)97(156)122-76(45(7)8)95(154)108-56(25-29-75(137)138)80(139)105-54(23-27-70(102)131)83(142)117-66(40-161)93(152)119-68(42-163)94(153)124-79(48(11)127)98(157)116-64(38-126)90(149)123-78(47(10)13-2)96(155)120-67(41-162)92(151)115-63(37-125)89(148)110-58(31-44(5)6)85(144)111-59(32-49-14-18-51(128)19-15-49)86(145)106-53(22-26-69(101)130)81(140)109-57(30-43(3)4)84(143)107-55(24-28-74(135)136)82(141)113-61(34-71(103)132)88(147)112-60(33-50-16-20-52(129)21-17-50)87(146)118-65(39-160)91(150)114-62(99(158)159)35-72(104)133/h18-26,31-36,40-47,69-70,77-88,98-118,126-130,199-203,241-242H,27-30,37-39,48-68,71-76,159-160H2,1-17H3,(H2,161,204)(H2,162,205)(H,165,171)(H,166,172)(H,168,215)(H,169,217)(H,170,216)(H,173,218)(H,174,206)(H,175,207)(H,176,208)(H,177,219)(H,178,228)(H,179,234)(H,180,237)(H,181,213)(H,182,226)(H,183,224)(H,184,227)(H,185,221)(H,186,223)(H,187,225)(H,188,220)(H,189,232)(H,190,235)(H,191,222)(H,192,236)(H,193,214)(H,194,230)(H,195,229)(H,196,231)(H,197,233)(H,209,210)(H,211,212)(H,239,240)(H4,163,164,167);14-21,43-48,53-68,76-79,125-129,160-163H,12-13,22-42,100H2,1-11H3,(H2,101,130)(H2,102,131)(H2,103,132)(H2,104,133)(H,105,139)(H,106,145)(H,107,143)(H,108,154)(H,109,140)(H,110,148)(H,111,144)(H,112,147)(H,113,141)(H,114,150)(H,115,151)(H,116,157)(H,117,142)(H,118,146)(H,119,152)(H,120,155)(H,121,134)(H,122,156)(H,123,149)(H,124,153)(H,135,136)(H,137,138)(H,158,159)/t86-,87+,88+,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,126-,127-,128-,129-,130-;46-,47-,48+,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,76-,77-,78-,79-/m00/s1

Synonyms:

• (Lys(B28),Pro(B29))-Humaninsulin
• 28B-L-Lysine-29B-L-Proline-Insulin(Human
• 28B-L-Lysine-29B-L-Prolineinsulin(Human)
• 8A-L-Threonine-10A-L-Isoleucine-28B-L-Lysine-29B-L-Proline-30B-Insulin(Ox
• Insulinlispro

INSULIN LISPRO CRS

CAS: 133107-64-9

INSULIN LISPRO CRS

Ref: 41-Y0000348

Insulin Lispro

CAS: 133107-64-9

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 5807.63

Ref: 45-1342321

Insulin lispro

CAS: 133107-64-9

Insulin lispro is a form of insulin that is used to treat diabetes. Insulin lispro contains a recombinant DNA molecule with a sequence identical to human insulin, and contains the same amino acid sequence as human insulin. It has two-way crossover, long-term efficacy, and low magnesium salt. The two-way crossover study was conducted on patients with diabetic neuropathy and showed an improved efficacy of oral hypoglycemic agents. The long-term efficacy of insulin lispro was demonstrated in a study that lasted for one year. Insulin lispro has been shown to be effective in the treatment of metabolic disorders such as diabetes and autoimmune diseases such as type 1 diabetes. Insulin lispro has been shown to have pharmacokinetic properties similar to those of human serum.

Formula: C₂₅₇H₃₈₉N₆₅O₇₇S₆

Purity: Min. 95%

Molecular weight: 5,814 g/mol

Ref: 3D-IFA10764