CAS 13311-84-7: Flutamide
Description:Flutamide is a non-steroidal antiandrogen medication primarily used in the treatment of prostate cancer. It functions by inhibiting the action of androgens, such as testosterone, at the cellular level, thereby slowing the growth of hormone-sensitive tumors. Flutamide is typically administered orally and is often used in combination with other therapies, such as surgical castration or luteinizing hormone-releasing hormone (LHRH) agonists, to enhance its efficacy. The compound has a molecular formula that includes carbon, hydrogen, nitrogen, and oxygen, reflecting its organic nature. Flutamide is known for its relatively high bioavailability and is metabolized in the liver, with its metabolites contributing to its therapeutic effects. Common side effects may include gastrointestinal disturbances, liver function abnormalities, and potential impacts on fertility. Due to its mechanism of action, flutamide is contraindicated in women who are pregnant or breastfeeding. As with any medication, its use should be closely monitored by healthcare professionals to manage potential adverse effects and interactions with other drugs.
Formula:C11H11F3N2O3
InChI:InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
InChI key:InChIKey=MKXKFYHWDHIYRV-UHFFFAOYSA-N
SMILES:O=C(NC1=CC=C(C(=C1)C(F)(F)F)N(=O)=O)C(C)C
- Synonyms:
- 2-Methyl-N-[4-nitro-3-(trifluoromethyl)-phenyl]-propionamide
- 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
- 4'-Nitro-3'-trifluoromethylisobutyranilide
- 4-Nitro-3-(trifluoromethyl)isobutyranilide
- Euflex
- Eulexin
- Flucinom
- Flutamid
- Flutamida
- Flutopharm
- See more synonyms
- Grisetin
- N-(Isopropylcarbonyl)-4-nitro-3-trifluoromethylaniline
- Niftholide
- Niftolide
- Nsc 147834
- Nsc 215876
- Odyne
- Propanamide, 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-
- Sch 13521
- m-Propionotoluidide, α,α,α-trifluoro-2-methyl-4'-nitro-