CAS 133156-06-6

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

Description:

Delta-Aminovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2, identified by its CAS number 133156-06-6, is a synthetic peptide that exhibits characteristics typical of peptide compounds. It is composed of a sequence of amino acids, which contributes to its biological activity and potential applications in pharmacology. The presence of specific amino acid residues, such as phenylalanine (Phe), proline (Pro), leucine (Leu), and methionine (Met), suggests that this peptide may have unique structural and functional properties, including potential interactions with biological receptors or enzymes. The N-methylation of the leucine residue may enhance its stability and bioavailability. Peptides like this one are often studied for their roles in signaling pathways, therapeutic applications, and as potential drug candidates. Additionally, the presence of an amine group at the terminal end indicates that it may participate in various chemical reactions or biological processes. Overall, the characteristics of this peptide make it a subject of interest in medicinal chemistry and biochemistry research.

Formula: C₄₀H₅₉N₇O₆S

InChI: InChI=1/C40H59N7O6S/c1-27(2)24-34(38(51)44-30(36(42)49)20-23-54-4)46(3)40(53)33-18-13-22-47(33)39(52)32(26-29-16-9-6-10-17-29)45-37(50)31(25-28-14-7-5-8-15-28)43-35(48)19-11-12-21-41/h5-10,14-17,27,30-34H,11-13,18-26,41H2,1-4H3,(H2,42,49)(H,43,48)(H,44,51)(H,45,50)/t30-,31-,32-,33-,34-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCSC)C(=N)O)O)N(C)C(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)N=C([C@H](Cc1ccccc1)N=C(CCCCN)O)O

Synonyms:

• Gr 73632
• H2H-(Ch2)4-Co-Phe-Pro-Nme-Leu-Met-Nh2
• (Delta-Aminovaleryl6,Pro9,N-Me-Leu10)-Substance P (6-11)
• Delta-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
• δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
• N-(5-aminopentanoyl)-L-phenylalanyl-L-phenylalanyl-L-prolyl-N-methyl-L-leucyl-L-methioninamide

L-Methioninamide, N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanyl-L-prolyl-N-methyl-L-leucyl-

CAS: 133156-06-6

Formula: C₄₀H₅₉N₇O₆S

Purity: 95%

Molecular weight: 766.0048

Ref: IN-DA0014CQ

GR-73632

CAS: 133156-06-6

GR-73632

Purity: ≥98%

Molecular weight: 766g/mol

Ref: 54-BUP04315

GR-73632

CAS: 133156-06-6

Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens).

Formula: C₄₀H₅₉N₇O₆S

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 766

Ref: TM-TP1572

GR 73632

CAS: 133156-06-6

GR 73632 is a neurokinin-1 receptor antagonist that has been shown to have an inhibitory effect on neurokinin-1 receptors. The binding of GR 73632 to the neurokinin-1 receptor leads to the inhibition of pressor responses and inflammatory diseases. It has also shown promise in treating cancer, as well as cervical cancer. GR 73632 binds to the wild-type mouse camp levels and inhibits the release of pressor peptides. This compound also acts as a selective agonist at the caudate putamen, which is involved in controlling blood pressure and urinary bladder function.

Formula: C₄₀H₅₉N₇O₆S

Purity: Min. 95%

Molecular weight: 766 g/mol

Ref: 3D-IFA15606