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CAS 1332075-63-4

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PI3kδ inhibitor 1

Description:
PI3Kδ inhibitor 1, identified by its CAS number 1332075-63-4, is a chemical compound that selectively inhibits the phosphoinositide 3-kinase delta (PI3Kδ) enzyme, which plays a crucial role in various cellular processes, including cell growth, proliferation, and survival. This inhibitor is particularly significant in the context of immunology and oncology, as PI3Kδ is predominantly expressed in leukocytes and is implicated in the signaling pathways of certain cancers and autoimmune diseases. The compound typically exhibits a high degree of specificity for PI3Kδ over other isoforms of PI3K, making it a valuable tool for research and potential therapeutic applications. Its mechanism of action involves binding to the active site of the enzyme, thereby preventing substrate phosphorylation and subsequent downstream signaling. In preclinical studies, PI3Kδ inhibitors have shown promise in modulating immune responses and inhibiting tumor growth, highlighting their potential in developing targeted therapies for diseases associated with dysregulated PI3K signaling.
Formula:C28H33FN6O2
Synonyms:
  • 2-d]pyrimidin-6-yl]methyl]piperidin-4-yl]propan-2-ol
  • 2-[1-[[2-(5-Fluoro-1H-indol-4-yl)-4-(Morpholin-4-yl)pyrido[3,2-d]pyriMidin-6-yl]Methyl]piperidin-4-yl]propan-2-ol
  • 2-[1-[[2-(5-Fluoro-1H-indol-4-yl)-4-(morpholin-4-yl)pyrido[3
  • PI3k-delta inhibitor 1
  • 4-PiperidineMethanol, 1-[[2-(5-fluoro-1H-indol-4-yl)-4-(4-Morpholinyl)pyrido[3,2-d]pyriMidin-6-yl]Methyl]-α,α-diMethyl-
  • 2-[1-[[2-(5-FLUORO-1H-INDOL-4-YL)-4-(MORPHOLIN-4-YL)PYRIDO[3;2-D]PYRIMIDIN-6-YL]METHYL]PIPERIDIN-4-YL]PROPAN-2-OL; 2-[1-[[2-(5-FLUORO-1H-INDOL-4-YL)-4-(MORPHOLIN-4-YL)PYRIDO[3;2-D]PYRIMIDIN-6-YL]METHYL]PIPERIDIN-4-YL]PROPAN-2-OL
  • PI3kδ inhibitor 1
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