CAS 133229-23-9

1-(4-methanesulfonamidophenoxy)-3-(N-methyl-3,4-dichlorophenylethylamino)-2-propanol

Description:

1-(4-Methanesulfonamidophenoxy)-3-(N-methyl-3,4-dichlorophenylethylamino)-2-propanol, with CAS number 133229-23-9, is a chemical compound that belongs to the class of beta-blockers, which are primarily used in the treatment of cardiovascular conditions. This compound features a complex structure characterized by a propanol backbone, a methanesulfonamide group, and a dichlorophenyl moiety, contributing to its pharmacological properties. It exhibits high lipophilicity, which enhances its ability to cross biological membranes, potentially affecting its bioavailability and distribution in the body. The presence of the methanesulfonamide group may also influence its solubility and interaction with biological targets. As a beta-blocker, it likely functions by antagonizing beta-adrenergic receptors, leading to effects such as reduced heart rate and decreased myocardial contractility. Understanding its specific pharmacodynamics and pharmacokinetics is crucial for evaluating its therapeutic efficacy and safety profile in clinical applications.

Formula: C₁₉H₂₄Cl₂N₂O₄S

InChI: InChI=1/C19H24Cl2N2O4S/c1-23(10-9-14-3-8-18(20)19(21)11-14)12-16(24)13-27-17-6-4-15(5-7-17)22-28(2,25)26/h3-8,11,16,22,24H,9-10,12-13H2,1-2H3

SMILES: CN(CCc1ccc(c(c1)Cl)Cl)CC(COc1ccc(cc1)NS(=O)(=O)C)O

Synonyms:

• Msaph-2ClPhEA-2-propanol
• N-(4-(3-((2-(3,4-Dichlorophenyl)ethyl)methylamino)-2-hydroxypropoxy)phenyl)methanesulfonamide
• Methanesulfonamide, N-(4-(3-((2-(3,4-dichlorophenyl)ethyl)methylamino)-2-hydroxypropoxy)phenyl)-
• N-[4-(3-{[2-(3,4-dichlorophenyl)ethyl](methyl)amino}-2-hydroxypropoxy)phenyl]methanesulfonamide