Δ2-Cefotetan is a synthetic antibiotic belonging to the cephalosporin class, characterized by its broad-spectrum activity against various Gram-positive and Gram-negative bacteria. It is particularly effective in treating infections caused by anaerobic bacteria. The compound features a β-lactam ring, which is essential for its antibacterial activity, and a unique side chain that enhances its stability against certain β-lactamases, enzymes produced by bacteria that confer resistance to β-lactam antibiotics. Δ2-Cefotetan is typically administered parenterally and is used in clinical settings for surgical prophylaxis and the treatment of intra-abdominal infections, among other indications. Its pharmacokinetic profile includes good tissue penetration and a relatively long half-life, allowing for less frequent dosing. As with other cephalosporins, potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood coagulation. Overall, Δ2-Cefotetan represents a valuable option in the arsenal of antibiotics, particularly in settings where resistant infections are a concern.

Δ2-Cefotetan

1332499-75-8: Δ2-Cefotetan is a synthetic antibiotic belonging to the cephalosporin class, characterized by its broad-spectrum activity against various Gram-positive and Gram-negative bacteria. It is particularly effective in treating infections caused by anaerobic bacteria. The compound features a β-lactam ring, which is essential for its antibacterial activity, and a unique side chain that enhances its stability against certain β-lactamases, enzymes produced by bacteria that confer resistance to β-lactam antibiotics. Δ2-Cefotetan is typically administered parenterally and is used in clinical settings for surgical prophylaxis and the treatment of intra-abdominal infections, among other indications. Its pharmacokinetic profile includes good tissue penetration and a relatively long half-life, allowing for less frequent dosing. As with other cephalosporins, potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood coagulation. Overall, Δ2-Cefotetan represents a valuable option in the arsenal of antibiotics, particularly in settings where resistant infections are a concern.

<p>Applications The Δ2-isomer of Cefotean (C242970). It is useful as intermediate in the preparation of cephalesorin compounds.<br>References Sugioka, T., et al.: Chem. Pharm. Bull., 38, 1998 (1990),<br></p>

CAS 1332499-75-8

Δ2-Cefotetan

δ2-Cefotetan

Ref: TR-C242965

Δ2-Cefotetan

Ref: ST-EA-CP-C378006