CAS 133305-89-2

(4′′R)-4′′-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4′′-deoxy-25-(1-methylethyl)avermectin A1a

Description:

The chemical substance known as (4′′R)-4′′-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4′′-deoxy-25-(1-methylethyl)avermectin A1a, with the CAS number 133305-89-2, is a derivative of avermectin, a class of macrocyclic lactones produced by the fermentation of the bacterium Streptomyces avermitilis. This compound exhibits potent anthelmintic and insecticidal properties, making it valuable in agricultural and veterinary applications. Its structure features multiple functional groups, including an acetylamino group and various alkyl substituents, which contribute to its biological activity. The presence of specific stereocenters in its molecular structure is crucial for its efficacy and selectivity against target organisms. Additionally, the compound's solubility, stability, and interaction with biological systems are influenced by its complex structure. As with many avermectins, it is important to handle this substance with care due to its potential toxicity to non-target organisms, including beneficial insects and aquatic life.

Formula: C₄₉H₇₃NO₁₄

InChI: InChI=1/C49H73NO14/c1-25(2)43-28(5)17-18-48(64-43)23-35-20-34(63-48)16-15-27(4)44(26(3)13-12-14-33-24-57-46-42(52)29(6)19-36(47(53)60-35)49(33,46)54)61-40-22-38(56-11)45(31(8)59-40)62-39-21-37(55-10)41(30(7)58-39)50-32(9)51/h12-15,17-19,25-26,28,30-31,34-46,52,54H,16,20-24H2,1-11H3,(H,50,51)/b13-12+,27-15+,33-14+/t26-,28-,30-,31-,34+,35-,36-,37-,38-,39-,40-,41+,42+,43+,44-,45-,46+,48+,49+/m0/s1

InChI key: InChIKey=WPNHOHPRXXCPRA-FZTOWWROSA-N

SMILES: [C@H](C)(C)[C@H]1O[C@@]2(C[C@@]3(C[C@](O2)(C/C=C(\C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@H](NC(C)=O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C\6/[C@@]7(O)[C@](C(=O)O3)(C=C(C)[C@@H](O)[C@]7(OC6)[H])[H])[H])[H])C=C[C@@H]1C

Synonyms:

• (4′′R)-4′′-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4′′-deoxy-25-(1-methylethyl)avermectin A_1a
• Avermectin A_1a, 4′′-(acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4′′-deoxy-25-(1-methylethyl)-, (4′′R)-
• Eprinomectin B1b
• Eprinomectin B_1b
• Eprinomectin Component B1b
• Eprinomectin component B_1b
• Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran], avermectin A_1a deriv.
• Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran], avermectin A1a deriv.
• Avermectin A1a, 4′′-(acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4′′-deoxy-25-(1-methylethyl)-, (4′′R)-
• (4′′R)-4′′-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4′′-deoxy-25-(1-methylethyl)avermectin A1a

Eprinomectin B1b

CAS: 133305-89-2

Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.

Formula: C₄₉H₇₃NO₁₄

Color and Shape: Solid

Molecular weight: 900.116

Ref: TM-T35738

Eprinomectin B1b

CAS: 133305-89-2

Formula: C₄₉H₇₃NO₁₄

Molecular weight: 900.12

Ref: 4Z-E-415

Eprinomectin B1b

Controlled Product

CAS: 133305-89-2

Formula: C₄₉H₇₃NO₁₄

Color and Shape: Neat

Molecular weight: 900.102

Ref: TR-E590053

Eprinomectin B1b-13CD3

Controlled Product

CAS: 133305-89-2

Formula: C₄₈CH₇₀D₃NO₁₄

Color and Shape: Neat

Molecular weight: 904.11

Ref: TR-E590054