CAS 133310-09-5

Fluphenazine b-D-Glucuronide

Description:

Fluphenazine b-D-Glucuronide is a chemical compound that serves as a metabolite of fluphenazine, an antipsychotic medication primarily used to treat schizophrenia and other psychotic disorders. This compound is characterized by its glucuronide conjugate structure, which enhances the solubility and excretion of fluphenazine in the body. Fluphenazine itself is a phenothiazine derivative, and its glucuronidation is a key metabolic pathway that facilitates its elimination. The presence of the glucuronide moiety typically indicates that the compound is more polar, which affects its pharmacokinetics and bioavailability. Fluphenazine b-D-Glucuronide is generally studied in the context of drug metabolism and pharmacology, particularly in understanding the metabolic pathways of antipsychotic medications. Its CAS number, 133310-09-5, is a unique identifier that allows for precise referencing in scientific literature and databases. Overall, this compound plays a significant role in the pharmacological profile of fluphenazine, influencing its therapeutic efficacy and safety profile.

Formula: C₂₈H₃₄F₃N₃O₇S

InChI: InChI=1/C28H34F3N3O7S/c29-28(30,31)17-6-7-21-19(16-17)34(18-4-1-2-5-20(18)42-21)9-3-8-32-10-12-33(13-11-32)14-15-40-27-24(37)22(35)23(36)25(41-27)26(38)39/h1-2,4-7,16,22-25,27,35-37H,3,8-15H2,(H,38,39)/t22-,23-,24+,25-,27+/m0/s1

Synonyms:

• 2-[4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl b-D-Glucopyranosiduronic Acid
• 7-Hydroxyfluphenazine Glucuronide
• 2-[4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl -D-Glucopyranosiduronic Acid
• Fluphenazine -D-Glucuronide
• 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl beta-D-glucopyranosiduronic acid

Fluphenazine b-D-Glucuronide

CAS: 133310-09-5

Formula: C₂₈H₃₄F₃N₃O₇S

Color and Shape: Solid

Molecular weight: 613.6457

Ref: IN-DA0014LG

Fluphenazine b-D-glucuronide

CAS: 133310-09-5

Ref: 7W-GC7885

Fluphenazine β-D-Glucuronide

Controlled Product

CAS: 133310-09-5

Formula: C₂₈H₃₄F₃N₃O₇S

Color and Shape: Neat

Molecular weight: 613.65

Ref: TR-F598410

Fluphenazine b-D-glucuronide

Controlled Product

CAS: 133310-09-5

Fluphenazine is a phenothiazine antipsychotic agent that is metabolized by the liver to form fluphenazine b-D-glucuronide. This compound has been shown to have high yield and an electron affinity. Fluphenazine b-D-glucuronide is a primary alcohol with a phenolic hydroxyl group. It can be synthesized using immobilized enzyme, which is an electron donor, and an aliphatic substrate such as methanol. The reaction product is incubated for six hours before it undergoes glucuronidation.

Formula: C₂₈H₃₄F₃N₃O₇S

Purity: Min. 95%

Molecular weight: 613.65 g/mol

Ref: 3D-MF10436

Fluphenazine β-D-Glucuronide

CAS: 133310-09-5

Formula: C₂₈H₃₄F₃N₃O₇S

Molecular weight: 613.65

Ref: ST-EA-CP-F33027