CAS 133352-27-9

lydicamycin

Description:

Lydicamycin is a naturally occurring antibiotic that belongs to the class of compounds known as macrolides. It is produced by certain strains of the bacterium *Micromonospora* and exhibits antibacterial properties, particularly against Gram-positive bacteria. The chemical structure of lydicamycin features a large lactone ring, which is characteristic of macrolide antibiotics, and it contains various functional groups that contribute to its biological activity. Lydicamycin is known for its ability to inhibit protein synthesis in bacteria by binding to the 50S ribosomal subunit, thereby interfering with the translation process. This mechanism of action makes it effective against a range of bacterial infections. Additionally, lydicamycin has been studied for its potential use in treating infections caused by resistant strains of bacteria. Its pharmacological profile includes considerations of solubility, stability, and bioavailability, which are crucial for its therapeutic application. Overall, lydicamycin represents an important compound in the field of antibiotic research and development.

Formula: C₄₇H₇₄N₄O₁₀

InChI: InChI=1/C47H74N4O10/c1-26(37(54)10-7-11-38(55)27(2)13-18-33(53)24-31-9-8-22-51(31)46(48)49)12-16-32(52)17-14-28(3)42(58)29(4)15-19-35-30(5)23-34-36(20-21-39(56)43(34)59)47(35,6)44(60)41-40(57)25-50-45(41)61/h7,10,12-14,16,23,26,29,31-39,42-43,50,52-56,58-59,61H,8-9,11,15,17-22,24-25H2,1-6H3,(H3,48,49)/b10-7+,16-12+,27-13-,28-14+

Synonyms:

• 1-Pyrrolidinecarboximidamide, 2-(21-(1-((2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl)carbonyl)-1,2,4a,5,6,7,8,8a-octahydro-5,6-dihydroxy-1,3-dimethyl-2-naphthalenyl)-2,6,10,14,18-pentahydroxy-5,11,17,19-tetramethyl-4,8,12,16-heneicosatetraenyl)-
• 2-[(4E,8E,12E,16E)-21-{(1R,2R,4aR,5S,6R,8aR)-5,6-dihydroxy-1-[(4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)carbonyl]-1,3-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-2-yl}-2,6,10,14,18-pentahydroxy-5,11,17,19-tetramethylhenicosa-4,8,12,16-tetraen-1-yl]pyrrolidine-1-carboximidamide
• 2-[(4Z,8E,12E,16E)-21-{5,6-dihydroxy-1-[(2-hydroxy-4-oxo-4,5-dihydro-1H-pyrrol-3-yl)carbonyl]-1,3-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-2-yl}-2,6,10,14,18-pentahydroxy-5,11,17,19-tetramethylhenicosa-4,8,12,16-tetraen-1-yl]pyrrolidine-1-carboximidamide
• Lydicamycin

Lydicamycin

CAS: 133352-27-9

Molecular weight: 855.11

Ref: 7W-GA8687

Lydicamycin

CAS: 133352-27-9

Lydicamycin is a new antibiotic isolated from the fermentation broth of an actinomycete strain identified as Streptomyces solani. Lydicamycin is active against Gram-positive bacteria and certain yeasts, but inactive against Gram-negative bacteria. Cost-effective and quality-assured.

Formula: C₄₇H₇₄N₄O₁₀

Color and Shape: Solid

Molecular weight: 855.127

Ref: TM-T33031

Lydicamycin

CAS: 133352-27-9

Lydicamycin is an antibacterial compound, which is a polyketide-derived antibiotic produced by the microorganism Streptomyces. This natural compound functions by inhibiting bacterial protein synthesis, effectively interrupting critical cellular processes within susceptible bacteria. The mode of action primarily focuses on binding to the bacterial ribosome, thereby disrupting protein production and inhibiting bacterial growth.

Formula: C₄₇H₇₄N₄O₁₀

Purity: Min. 95%

Molecular weight: 855.11 g/mol

Ref: 3D-AL184016