Stem Cell Factor (SCF), also known as Steel factor or Kit ligand, is a glycoprotein that plays a crucial role in hematopoiesis and the development of various cell types, particularly in the regulation of stem cells and their differentiation. It is primarily produced by stromal cells and acts through its receptor, c-KIT, which is expressed on hematopoietic stem cells and other progenitor cells. SCF is involved in several biological processes, including cell survival, proliferation, and migration. The human form of SCF is characterized by its ability to bind to c-KIT, leading to receptor dimerization and activation of downstream signaling pathways that promote cell growth and differentiation. This factor is essential in the maintenance of the hematopoietic stem cell niche and has implications in various medical conditions, including certain types of cancer and genetic disorders. Its CAS number, 133352-98-4, is used for identification in chemical databases and regulatory contexts. Overall, SCF is a vital component in the complex network of signals that govern cell fate and development.

STEM CELL FACTOR, HUMAN

133352-98-4: Stem Cell Factor (SCF), also known as Steel factor or Kit ligand, is a glycoprotein that plays a crucial role in hematopoiesis and the development of various cell types, particularly in the regulation of stem cells and their differentiation. It is primarily produced by stromal cells and acts through its receptor, c-KIT, which is expressed on hematopoietic stem cells and other progenitor cells. SCF is involved in several biological processes, including cell survival, proliferation, and migration. The human form of SCF is characterized by its ability to bind to c-KIT, leading to receptor dimerization and activation of downstream signaling pathways that promote cell growth and differentiation. This factor is essential in the maintenance of the hematopoietic stem cell niche and has implications in various medical conditions, including certain types of cancer and genetic disorders. Its CAS number, 133352-98-4, is used for identification in chemical databases and regulatory contexts. Overall, SCF is a vital component in the complex network of signals that govern cell fate and development.

rHuSCF

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CAS 133352-98-4

STEM CELL FACTOR, HUMAN

rHuSCF

Ref: 54-BIS2855

rec Stem Cell Factor (human)

Ref: 3D-FR108519