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CAS 133367-33-6

:

FMOC-HIS(MMT)-OH

Description:
FMOC-HIS(MMT)-OH, with the CAS number 133367-33-6, is a derivative of histidine, an essential amino acid. This compound features a 9-fluorenylmethoxycarbonyl (FMOC) protecting group, which is commonly used in peptide synthesis to protect the amino group of the amino acid during the coupling process. The MMT (4-methyltrityl) group is another protective group that shields the side chain of histidine, specifically the imidazole nitrogen, preventing unwanted reactions during synthesis. FMOC-HIS(MMT)-OH is typically utilized in solid-phase peptide synthesis, allowing for the selective assembly of peptides while maintaining the integrity of functional groups. The compound is generally stable under standard laboratory conditions but may require specific handling to avoid degradation. Its solubility is typically in organic solvents, making it suitable for various synthetic applications. Overall, FMOC-HIS(MMT)-OH is a valuable intermediate in the production of peptides and proteins, contributing to advancements in biochemistry and pharmaceutical research.
Formula:C41H35N3O5
InChI:InChI=1/C41H35N3O5/c1-48-32-22-20-30(21-23-32)41(28-12-4-2-5-13-28,29-14-6-3-7-15-29)44-25-31(42-27-44)24-38(39(45)46)43-40(47)49-26-37-35-18-10-8-16-33(35)34-17-9-11-19-36(34)37/h2-23,25,27,37-38H,24,26H2,1H3,(H,43,47)(H,45,46)/t38-/m0/s1
SMILES:COc1ccc(cc1)C(c1ccccc1)(c1ccccc1)n1cc(C[C@@H](C(=O)O)N=C(O)OCC2c3ccccc3c3ccccc23)nc1
Synonyms:
  • N-Alpha-Fmoc-Nim-(4-Methoxytrityl)-L-Histidine
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N-Im-P-Methoxytrityl-L-Histidine
  • N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Tau-Monomethoxytrityl-L-Histidine
  • N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Tau-4-Methoxytrityl-L-Histidine
  • Fmoc-L-His(Mmt)-Oh
  • Fmoc-His(Meotrt)-Oh
  • Fmoc-Nim-(4-Methoxytrityl)-L-Histidine
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-((4-methoxyphenyl)-diphenylmethyl)-1H-i
  • Nα-Fmoc-Nim-methoxytrityl-L-histidine
  • N-alpha-FMoc-N-iM-Methoxytrityl-L-histidine
  • See more synonyms
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