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CAS 133367-34-7

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N(alpha)-fmoc-N(im)-(4-methyltrityl)-L-histidine

Description:
N(alpha)-fmoc-N(im)-(4-methyltrityl)-L-histidine is a modified amino acid commonly used in peptide synthesis and research. This compound features a histidine residue, which is an essential amino acid known for its role in enzyme active sites and metal ion coordination. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, facilitating the stepwise synthesis of peptides by preventing unwanted reactions. The "4-methyltrityl" group provides additional protection for the imidazole side chain of histidine, enhancing stability during synthesis. This compound is typically used in solid-phase peptide synthesis, where the protection of functional groups is crucial for the successful assembly of complex peptides. Its unique structure allows for specific interactions in biological systems, making it valuable in the development of pharmaceuticals and bioconjugates. Overall, N(alpha)-fmoc-N(im)-(4-methyltrityl)-L-histidine is characterized by its protective groups, stability, and utility in peptide chemistry.
Formula:C41H35N3O4
Synonyms:
  • Fmoc-His(Mtt)-OH
  • N-alpha-(9-fluorenylmethyloxycarbonyl)-N-im-p-methyltrityl-L-histidine
  • FMOC-HISTIDINE(MTT)-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl His(Mtt)-OH
  • N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-N-IM-P-METHYLTRITYL-L-HISTIDINE
  • FMOC-N-IM-METHYLTRITYL-L-HISTIDINE
  • N(ALPHA)-FMOC-N(IM)-(4-METHYLTRITYL)-
  • L-Histidine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-1-[(4-methylphenyl)diphenylmethyl]-
  • FMoc-His(t-Mtt)-OH
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(4-methylphenyl)-diphenylmethyl]imidazol-4-yl]propanoic acid
  • See more synonyms
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