CAS 1334169-90-2

MPEG8-NH-Mal

Description:

MPEG8-NH-Mal, or Methoxy Polyethylene Glycol (MPEG) with a molecular weight of approximately 8 kDa, is a derivative of polyethylene glycol (PEG) that features a maleimide functional group. This compound is characterized by its hydrophilic nature due to the presence of the polyethylene glycol backbone, which enhances solubility in aqueous environments. The maleimide group allows for specific conjugation reactions, making MPEG8-NH-Mal useful in bioconjugation applications, such as drug delivery systems and the development of biopharmaceuticals. The presence of the amine group (NH) provides additional reactivity, facilitating the formation of stable linkages with various biomolecules, including proteins and peptides. MPEG8-NH-Mal is typically utilized in the synthesis of polymer-drug conjugates, where it can improve the pharmacokinetics and bioavailability of therapeutic agents. Its biocompatibility and ability to form covalent bonds with thiol-containing compounds make it a valuable tool in the fields of medicinal chemistry and materials science.

Formula: C₂₄H₄₂N₂O₁₁

InChI: InChI=1S/C24H42N2O11/c1-30-8-9-32-12-13-34-16-17-36-20-21-37-19-18-35-15-14-33-11-10-31-7-5-25-22(27)4-6-26-23(28)2-3-24(26)29/h2-3H,4-21H2,1H3,(H,25,27)

InChI key: DYKKRMSENAYADQ-UHFFFAOYSA-N

SMILES: COCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

Synonyms:

• m-dPEG(R)8-MAL
• m-PEG8-amido-Mal
• 1334169-90-2
• MPEG8-NH-Mal
• Mal-amido-PEG8-Ome
• m-dPEG8-MAL
• mPEG8-Maleimide
• m-PEG8-Mal
• 1H-Pyrrole-1-propanamide, 2,5-dihydro-N-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl-2,5-dioxo-

m-PEG8-Mal

CAS: 1334169-90-2

m-PEG8-Mal

Formula: C₂₄H₄₂N₂O₁₁

Purity: 98%

Molecular weight: 534.59707

Ref: 54-BIPG1613

mPEG8-Mal

CAS: 1334169-90-2

Formula: C₂₄H₄₂N₂O₁₁

Purity: 98%

Molecular weight: 534.5971

Ref: IN-DA009ITA

m-PEG8-Mal

CAS: 1334169-90-2

m-PEG8-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Formula: C₂₄H₄₂N₂O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 534.6

Ref: TM-T15934

m-PEG8-Mal

CAS: 1334169-90-2

3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)propanamide

Formula: C₂₄H₄₂N₂O₁₁

Purity: 98%

Molecular weight: 534.6

Ref: IN-DG00833988

MAL-dPEG®8-TFP Ester

CAS: 1334169-90-2

MAL-dPEG®8-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®8-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₅₈H₉₁N₅O₁₉S

Purity: Min. 95%

Molecular weight: 1,194.43 g/mol

Ref: 3D-DPG-6221