CAS 1334169-95-7

dPEG(R)12-SATA (S-acetyl-dPEG(R)12-NHS ester)

Description:

dPEG(R)12-SATA, also known as S-acetyl-dPEG(R)12-NHS ester, is a specialized chemical compound used primarily in bioconjugation and drug delivery applications. It features a polyethylene glycol (PEG) backbone, which enhances solubility and biocompatibility, making it suitable for use in biological systems. The "12" in its name indicates the presence of a 12-unit PEG chain, which contributes to its hydrophilicity and reduces non-specific interactions with proteins and cells. The NHS (N-hydroxysuccinimide) ester functionality allows for efficient conjugation to amine-containing molecules, such as proteins or peptides, facilitating the formation of stable amide bonds. The acetyl group provides a protective mechanism that can be removed under mild conditions, allowing for controlled release or activation of the conjugated species. Overall, dPEG(R)12-SATA is valued for its versatility in creating targeted therapeutics and diagnostic agents, owing to its ability to improve the pharmacokinetic properties of conjugated molecules while maintaining biological activity.

Formula: C₃₃H₅₉NO₁₇S

Synonyms:

• dPEG(R)12-SATA (S-acetyl-dPEG(R)12-NHS ester)
• -SATA (S-acetyl-dPEG
• -NHS ester)
• 12
• &reg
• α-Acethylthio-omega-(succinimidyl propionate) hexadeca(ethylene glycol)
• dPEG? 12-SATA (S-acetyl-dPEG? 12-NHS ester)
• dPEG

2,5-Dioxopyrrolidin-1-yl 2-oxo-6,9,12,15,18,21,24,27,30,33,36,39-dodecaoxa-3-thiadotetracontan-42-oate

CAS: 1334169-95-7

Formula: C₃₃H₅₉NO₁₇S

Purity: 95%

Molecular weight: 773.8831

Ref: IN-DA00VR4E

2,5-Dioxopyrrolidin-1-yl 2-oxo-6,9,12,15,18,21,24,27,30,33,36,39-dodecaoxa-3-thiadotetracontan-42-oate

CAS: 1334169-95-7

2,5-Dioxopyrrolidin-1-yl 2-oxo-6,9,12,15,18,21,24,27,30,33,36,39-dodecaoxa-3-thiadotetracontan-42-oate

Purity: 98%

Molecular weight: 773.89g/mol

Ref: 54-OR1067566

Ac-S-dpeg(12)-NHS

CAS: 1334169-95-7

Ac-S-dpeg(12)-NHS is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Ac-S-dpeg(12)-NHS is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₃₃H₅₉NO₁₇S

Purity: Min. 95%

Molecular weight: 773.9 g/mol

Ref: 3D-JDC16995