CAS 133429-58-0

L-Leucinamide,N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-

Description:

L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]- is a synthetic compound that belongs to the class of amino acid derivatives. It features a leucine backbone, which is an essential branched-chain amino acid, and is modified with various functional groups, including a phenylmethoxycarbonyl group and a formyl-phenylethyl moiety. This structure suggests potential applications in medicinal chemistry, particularly in the development of peptide-based therapeutics or as a building block in the synthesis of more complex molecules. The presence of the phenyl groups may enhance lipophilicity, potentially influencing the compound's bioavailability and interaction with biological targets. Additionally, the specific stereochemistry indicated by the (1S) configuration suggests that the compound may exhibit unique biological activity or selectivity. As with many amino acid derivatives, the compound may also participate in various chemical reactions, including peptide bond formation, making it of interest in both organic synthesis and pharmaceutical development. Further studies would be necessary to elucidate its specific properties and potential applications.

Formula: C₂₉H₃₉N₃O₅

Z-Leu-Leu-Phe-CHO

CAS: 133429-58-0

Formula: C₂₉H₃₉N₃O₅

Molecular weight: 509.7

Ref: 7W-GL3344

Z-Leu-Leu-Phe-cho

CAS: 133429-58-0

Z-Leu-Leu-Phe-cho is a synthetic conjugate that has been shown to protect against HIV infection in an experimental model. Z-Leu-Leu-Phe-cho is a glycopolymer that inhibits the expression of Toll-like receptor 4 (TLR4) on the surface of cells, thereby preventing activation of the TLR4 signalling cascade. This reduces the production of inflammatory cytokines, which may be involved in cancer and other diseases. The effective dose was found to be 1 mg/kg by intravenous injection in Sprague Dawley rats.

Formula: C₂₉H₃₉N₃O₅

Purity: Min. 95%

Molecular weight: 509.6 g/mol

Ref: 3D-IFA42958

Z-LLF-CHO

CAS: 133429-58-0

Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.

Formula: C₂₉H₃₉N₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 509.64

Ref: TM-T78640