CAS 133432-71-0

Peldesine

Description:

Peldesine, with the CAS number 133432-71-0, is a synthetic nucleoside analog that has been investigated primarily for its potential antiviral and anticancer properties. It is characterized by its ability to inhibit viral replication and interfere with nucleic acid synthesis, making it a candidate for treating various viral infections and certain types of cancer. The compound exhibits a unique structure that allows it to mimic natural nucleosides, which is crucial for its mechanism of action. Peldesine has shown activity against a range of viruses, including those in the herpesvirus family. Its pharmacological profile includes considerations of bioavailability, metabolism, and toxicity, which are essential for evaluating its therapeutic potential. Research into Peldesine continues to explore its efficacy, optimal dosing regimens, and potential side effects, contributing to the broader field of antiviral and anticancer drug development. As with many experimental compounds, further clinical studies are necessary to fully understand its benefits and limitations in medical applications.

Formula: C₁₂H₁₁N₅O

InChI: InChI=1S/C12H11N5O/c13-12-16-9-8(4-7-2-1-3-14-5-7)6-15-10(9)11(18)17-12/h1-3,5-6,15H,4H2,(H3,13,16,17,18)

InChI key: InChIKey=DOHVAKFYAHLCJP-UHFFFAOYSA-N

SMILES: C(C=1C2=C(NC1)C(=O)N=C(N)N2)C=3C=CC=NC3

Synonyms:

• 2-Amino-3,5-dihydro-7-(3-pyridinylmethyl)-4H-pyrrolo[3,2-d]pyrimidin-4-one
• 2-Amino-3,5-dihydro-7-(3-pyridylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-one
• 2-Amino-7-(3-pyridylmethyl)-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidine
• 2-amino-7-(pyridin-3-ylmethyl)-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
• 4H-Pyrrolo(3,2-d)pyrimidin-4-one, 2-amino-3,5-dihydro-7-(3-pyridinylmethyl)-
• 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro-7-(3-pyridinylmethyl)-
• 9-(3-Pyridylmethyl)-7H-9-deazaguanine
• Bcx-34
• Peldesine [USAN]
• Unii-7B646Rj70F
• Peldesine

Peldesine

CAS: 133432-71-0

Peldesine

Purity: ≥98%

Molecular weight: 241.25g/mol

Ref: 54-BUP12520

Peldesine

CAS: 133432-71-0

Peldesine is a ligand that binds to and activates ion channels. It has been shown to activate the nicotinic acetylcholine receptor, alpha-adrenergic receptors, and serotonin receptors. Peldesine is also used as a research tool in cell biology because it can bind to proteins without affecting their function. This drug can inhibit protein interactions by competing with other ligands for binding sites on the target protein.

Formula: C₁₂H₁₁N₅O

Purity: Min. 95%

Molecular weight: 241.25 g/mol

Ref: 3D-IFA43271

Peldesine

CAS: 133432-71-0

Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.

Formula: C₁₂H₁₁N₅O

Purity: 99.27% - 99.9%

Color and Shape: Solid

Molecular weight: 241.25

Ref: TM-T12399