CAS 13345-51-2

prostaglandin B(1)

Description:

Prostaglandin B(1) is a bioactive lipid compound that plays a significant role in various physiological processes within the body. It is a member of the prostaglandin family, which are derived from arachidonic acid and are involved in mediating inflammation, regulating blood flow, and influencing the immune response. Prostaglandin B(1) is characterized by its unique structure, which includes a cyclopentane ring and multiple functional groups that contribute to its biological activity. It is known for its vasodilatory effects, which can help in the regulation of blood pressure and enhance blood flow to tissues. Additionally, prostaglandin B(1) has been studied for its potential therapeutic applications, including its role in gastrointestinal protection and its effects on reproductive health. Due to its complex nature and involvement in various biochemical pathways, prostaglandin B(1) is of interest in pharmacology and medical research, particularly in the context of inflammatory diseases and cardiovascular health.

Formula: C₂₀H₃₂O₄

InChI: InChI=1/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,17,21H,2-11,13,15H2,1H3,(H,23,24)/b14-12+/t17-/m0/s1

InChI key: InChIKey=YBHMPNRDOVPQIN-VSOYFRJCSA-N

SMILES: C(CCCCCC(O)=O)C1=C(/C=C/[C@H](CCCCC)O)CCC1=O

Synonyms:

• (13E,15S)-15-hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid
• 1-Cyclopentene-1-heptanoic acid, 2-(3-hydroxy-1-octenyl)-5-oxo-
• 15-Hydroxy-9-Oxoprosta-8(12),13-Dien-1-Oic Acid
• 15-Hydroxy-9-oxoprosta-8(12),13-dienoic acid
• 15α-Hydroxy-9-ketoprosta-8(12),13-dienoic acid
• 15α-Hydroxy-9-oxo-8(12),13E-prostadienoic acid
• PGB₁
• PGE₁-278
• Prosta-8(12),13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-
• Prostaglandin B₁
• Prostaglandin E₁-278
• Prostaglandin�B1
• prostaglandin B1
• PGB1
• 9-OXO-15S-HYDROXY-PROSTA-8(12),13E-DIEN-1-OIC ACID
• 15-epi-PGB1
• PROSTAGLANDINS B1
• 7-[2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-1-cyclopentenyl]heptanoic acid
• ProstaglandinB1,(13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid, PGB1
• Prostaglandin Impurity B
• Prostaglandin B1 ((13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic Acid) (1578554)
• (+)-2-[(E,R)-3-Hydroxy-1-octenyl]-5-oxo-1-cyclopentene-1-heptanoic acid
• Alprostadil (Prostaglandin E1) EP Impurity B
• Prostaglandin E1-278
• (13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid, PGB1
• PGE1-278
• (-)-(E)-Prostaglandin E1-278
• [13E,15R,(+)]-15-Hydroxy-9-oxo-8,12-didehydroprost-13-en-1-oic acid

Prostaglandin B1 ((13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid)

CAS: 13345-51-2

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

Formula: C₂₀H₃₂O₄

Color and Shape: White Off-White Solid

Molecular weight: 336.23006

Ref: 45-1578554

(13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid

CAS: 13345-51-2

Formula: C₂₀H₃₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 336.4657

Ref: IN-DA0072MU

Prostaglandin B1

CAS: 13345-51-2

Prostaglandin B1 (PGB1), a metabolite of Prostaglandin E1, acts as a prostanoid receptor ligand [1] [2].

Formula: C₂₀H₃₂O₄

Molecular weight: 336.47

Ref: TM-TN7771

Prostaglandin B1 synthetic

CAS: 13345-51-2

Formula: C₂₀H₃₂O₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 336.47

Ref: 7W-GK4431

Alprostadil (Prostaglandin E1) EP Impurity B

CAS: 13345-51-2

Formula: C₂₀H₃₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 336.47

Ref: 4Z-P-144008

Prostaglandin B1

CAS: 13345-51-2

Stability Light Sensitive
Applications Prostaglandin B1 is a novel microbial biopolymer which has been shown to improve the longevity of type 2 diabetic rodents. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.
References Yeo, J. et al.: J. Microbiol. Biotech., 17, 1983 (2007); Rosenthal, M. et al.: Biochim. Biophys. Act. Lip. Lip Met., 1006, 278 (1989);

Formula: C₂₀H₃₂O₄

Color and Shape: Light Yellow

Molecular weight: 336.47

Ref: TR-P838560

Postaglandin B1

CAS: 13345-51-2

Postaglandin B1 is a surfactant that has been shown to inhibit the production of prostaglandin E2 (PGE2) in wild-type strains. This inhibition leads to a decrease in the levels of PGE2, which are involved in the pathogenic mechanism and cause hypersecretion of mucous. The enzyme activities of phospholipase A2, cyclooxygenase, and lipoxygenase were also inhibited by postaglandin B1. Postaglandin B1 also showed a significant hypoglycemic effect when administered to mice at physiological levels. This drug also inhibits transcriptional regulation and protein synthesis in the presence of hydrophobic molecules.

Formula: C₂₀H₃₂O₄

Purity: Min. 95%

Molecular weight: 336.47 g/mol

Ref: 3D-FP171300

Alprostadil EP Impurity B

CAS: 13345-51-2

Formula: C₂₀H₃₂O₄

Molecular weight: 336.47

Ref: ST-EA-CP-A124002