CAS 1334513-10-8

N-[[P(S),2′R]-2′-Deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-cytidylyl]-L-alanine 1-methylethyl ester

Description:

N-[[P(S),2′R]-2′-Deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-cytidylyl]-L-alanine 1-methylethyl ester is a complex chemical compound that belongs to the class of nucleotides and their derivatives. This substance features a modified cytidine structure, which includes a deoxy sugar moiety and a fluorinated methyl group, contributing to its unique properties. The presence of the L-alanine moiety suggests potential biological activity, possibly influencing peptide synthesis or interactions with nucleic acids. The compound's esterification with 1-methylethyl indicates that it may exhibit enhanced lipophilicity, potentially affecting its solubility and permeability in biological systems. The specific stereochemistry denoted by the P(S) and 2′R configurations implies that the compound may have distinct chiral properties, which can influence its biological interactions and pharmacological profile. Overall, this compound may be of interest in medicinal chemistry and biochemistry, particularly in the development of nucleoside analogs or therapeutic agents targeting specific biological pathways.

Formula: C₂₂H₃₀FN₄O₈P

InChI: InChI=1S/C22H30FN4O8P/c1-13(2)33-19(29)14(3)26-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)27-11-10-17(24)25-21(27)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,26,31)(H2,24,25,30)/t14-,16+,18+,20+,22+,36-/m0/s1

InChI key: InChIKey=JMTNHBQFZOWQKE-IQWMDFIBSA-N

SMILES: C[C@]1(F)[C@@H](O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OC(C)C)=O)C)=O)[C@H]1O)N3C(=O)N=C(N)C=C3

Synonyms:

• N-[[P(S),2′R]-2′-Deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-cytidylyl]-L-alanine 1-methylethyl ester
• L-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-cytidylyl]-, 1-methylethyl ester
• ZL-01 metabolite M1

Sofosbuvir impurity J

CAS: 1334513-10-8

Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.

Formula: C₂₂H₃₀FN₄O₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 528.47

Ref: TM-T12965

Sofosbuvir Impurity 119

CAS: 1334513-10-8

Formula: C₂₂H₃₀FN₄O₈P

Molecular weight: 528.47

Ref: 4Z-S-055128

Sofosbuvir impurity J

CAS: 1334513-10-8

Sofosbuvir impurity J is a chemical impurity that arises during the synthesis of Sofosbuvir, an antiviral medication primarily used in the treatment of hepatitis C. This impurity is a byproduct produced during the manufacturing process of Sofosbuvir, originating from its chemical synthesis pathway.

Formula: C₂₂H₃₀FN₄O₈P

Purity: Min. 95%

Molecular weight: 528.5 g/mol

Ref: 3D-JDC51310

Sofosbuvir Impurity 89

CAS: 1334513-10-8

Formula: C₂₂H₃₀FN₄O₈P

Molecular weight: 528.5

Ref: ST-EA-CP-S45062