Eglin C (42-45)-methyl ester is a synthetic derivative of Eglin C, a potent inhibitor of serine proteases, which are enzymes that play critical roles in various biological processes, including digestion, immune response, and blood coagulation. This compound is characterized by its ability to selectively inhibit specific proteases, making it valuable in biochemical research and potential therapeutic applications. The methyl ester modification enhances its stability and bioavailability compared to the parent compound. Eglin C and its derivatives are often studied for their roles in drug development, particularly in designing inhibitors for diseases where protease activity is dysregulated. The compound's structure includes a peptide backbone with specific amino acid residues that contribute to its inhibitory activity. Additionally, its CAS number, 133463-25-9, allows for precise identification in chemical databases and literature. Overall, Eglin C (42-45)-methyl ester represents a significant tool in the study of protease inhibition and its implications in health and disease.

Eglin c (42-45)-methyl ester

133463-25-9: Eglin C (42-45)-methyl ester is a synthetic derivative of Eglin C, a potent inhibitor of serine proteases, which are enzymes that play critical roles in various biological processes, including digestion, immune response, and blood coagulation. This compound is characterized by its ability to selectively inhibit specific proteases, making it valuable in biochemical research and potential therapeutic applications. The methyl ester modification enhances its stability and bioavailability compared to the parent compound. Eglin C and its derivatives are often studied for their roles in drug development, particularly in designing inhibitors for diseases where protease activity is dysregulated. The compound's structure includes a peptide backbone with specific amino acid residues that contribute to its inhibitory activity. Additionally, its CAS number, 133463-25-9, allows for precise identification in chemical databases and literature. Overall, Eglin C (42-45)-methyl ester represents a significant tool in the study of protease inhibition and its implications in health and disease.

Eglin C (42-45)-methyl ester·HCl H-Pro-Val-Thr-Leu-OMe·HCl is a nonapeptide that has inhibitory effects on human leukocyte enzymes, such as cathepsin G. It inhibits the activity of the enzyme by binding to it and preventing the enzyme from carrying out its function. This drug also has inhibitory effects on other leukocyte enzymes, such as cathepsin L and elastase. Eglin C (42-45)-methyl ester·HCl H-Pro-Val-Thr-Leu-OMe·HCl also has inhibitory effects on human cathepsin D. The drug has been shown to have inhibitory activity against both mouse and human leukocyte cell lines, with more potent activity in human cells than in mouse cells.

CAS 133463-25-9

Eglin c (42-45)-methyl ester

Eglin c (42-45)-methyl ester·HCl

Ref: 3D-FE108375