CAS 1335042-50-6

3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3,4-dimethyl-4-pentenoic acid

Description:

3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3,4-dimethyl-4-pentenoic acid, commonly referred to as Fmoc-DM-4-pentenoic acid, is a synthetic organic compound primarily used in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under acidic conditions. The presence of the dimethyl and pentenoic acid moieties contributes to its unique reactivity and solubility properties. The structure includes an amino group, which is essential for peptide bond formation, and a carboxylic acid group, which plays a critical role in the acid-base chemistry of the compound. Its molecular characteristics make it suitable for applications in biochemistry and medicinal chemistry, particularly in the synthesis of complex peptides and proteins. As with many synthetic compounds, handling should be done with care, following appropriate safety protocols to mitigate any potential hazards.

Formula: C₂₂H₂₃NO₄

InChI: InChI=1S/C22H23NO4/c1-14(2)22(3,12-20(24)25)23-21(26)27-13-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19H,1,12-13H2,2-3H3,(H,23,26)(H,24,25)

InChI key: InChIKey=FWENTROLZFINEH-UHFFFAOYSA-N

SMILES: C(NC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)(CC(O)=O)(C(C)=C)C

Synonyms:

• 3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3,4-dimethyl-4-pentenoic acid
• 4-Pentenoic acid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3,4-dimethyl-
• 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,4-dimethylpent-4-enoic acid