CymitQuimica logo

CAS 133525-12-9

:

N-succinyl-ile-ile-trp 7-amido-4-*methylcoumarin

Description:
N-succinyl-ile-ile-trp 7-amido-4-methylcoumarin is a synthetic compound that belongs to the class of peptide substrates and is often used in biochemical research, particularly in studies involving proteases and enzyme activity. This compound features a succinyl group, which enhances its solubility and stability, and is linked to a peptide sequence that includes isoleucine and tryptophan, contributing to its specificity for certain enzymes. The 7-amido-4-methylcoumarin moiety serves as a fluorogenic tag, allowing for the detection of enzymatic activity through fluorescence. This characteristic makes it valuable in assays where monitoring enzyme kinetics is essential. The compound is typically soluble in organic solvents and exhibits stability under physiological conditions, although it may be sensitive to extreme pH or temperature variations. Its applications extend to drug discovery and the development of diagnostic tools, where understanding proteolytic activity is crucial. As with many synthetic peptides, proper handling and storage conditions are necessary to maintain its integrity and functionality in experimental settings.
Formula:C37H45N5O8
InChI:InChI=1/C37H45N5O8/c1-6-20(3)33(40-30(43)14-15-31(44)45)36(48)41-34(21(4)7-2)37(49)42-35(47)28(17-23-19-38-27-11-9-8-10-26(23)27)39-24-12-13-25-22(5)16-32(46)50-29(25)18-24/h8-13,16,18-21,28,33-34,38-39H,6-7,14-15,17H2,1-5H3,(H,40,43)(H,41,48)(H,44,45)(H,42,47,49)/t20-,21-,28-,33-,34-/m0/s1
SMILES:CC[C@H](C)[C@@H](C(=N[C@@H]([C@@H](C)CC)C(=O)N=C([C@H](Cc1c[nH]c2ccccc12)Nc1ccc2c(C)cc(=O)oc2c1)O)O)N=C(CCC(=O)O)O
Synonyms:
  • Succinyl-isoleucyl-isoleucyl-tryptophyl-methylcoumarinamide
  • N-(3-Carboxy-1-oxopropyl)-L-isoleucyl-L-isoleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tryptophanamide
  • Suc-ile-ile-trp-mca
  • Succinyl-ile-ile-trp-methylcoumarinamide
  • L-Tryptophanamide, N-(3-carboxy-1-oxopropyl)-L-isoleucyl-L-isoleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
  • N-(3-carboxypropanoyl)-L-isoleucyl-N-{(2S)-3-(1H-indol-3-yl)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]propanoyl}-L-isoleucinamide
  • N-Succinyl-Ile-Ile-Trp 7-Amido-4-Methylcoumarin
  • SUCCINYL-L-ISOLEUCYL-L-ISOLEUCYL-L-TRYPTOPHAN 4-METHYLCOUMARYL-7-AMIDE
  • N-SUCCINYL-ILE-ILE-TRP-AMC
  • SUCCINYL-ILE-ILE-TRP-AMC
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
  • N-Succinyl-Ile-Ile-Trp-7-amido-4-methylcoumarin
    Glentham
    + Info

    N-Succinyl-Ile-Ile-Trp-7-amido-4-methylcoumarin

    CAS:
    Molecular weight:687.78

    Ref: 7W-GM7754

    ne
    To inquire
  • Suc-Ile-Ile-Trp-MCA
    Biosynth
    + Info

    Suc-Ile-Ile-Trp-MCA

    CAS:
    <p>Suc-Ile-Ile-Trp-MCA is a peptide that is used as a research tool to study protein interactions and receptor function. This peptide can be used to inhibit ion channels and act as an activator of certain proteins. Suc-Ile-Ile-Trp-MCA binds to the N terminus of the alpha subunit of the G protein, which has been shown to activate the enzyme adenylate cyclase. It also binds to other receptors, such as the beta 2 adrenergic receptor in erythrocytes that leads to increased levels of cAMP. The selectivity for these binding sites is not yet known.</p>
    Formula:C37H45N5O8
    Purity:Min. 95%
    Molecular weight:687.78 g/mol

    Ref: 3D-MIW-3150-V

    5mg
    320.00€