CAS 133550-37-5

TYRPHOSTIN AG 835

Description:

Tyrphostin AG 835 is a synthetic compound that acts as a selective inhibitor of receptor tyrosine kinases, particularly targeting the epidermal growth factor receptor (EGFR) and other related kinases. It is primarily utilized in biochemical research to study signal transduction pathways and cellular processes influenced by tyrosine phosphorylation. The compound is characterized by its ability to interfere with cell proliferation and survival mechanisms, making it a valuable tool in cancer research and drug development. Tyrphostin AG 835 is typically used in vitro to assess the effects of tyrosine kinase inhibition on various cellular responses. Its chemical structure includes specific functional groups that contribute to its inhibitory activity, and it is often employed in studies related to tumor biology and therapeutic resistance. As with many research chemicals, proper handling and safety precautions are essential, as the compound may pose health risks if not managed appropriately.

Formula: C₁₈H₁₆N₂O₃

InChI: InChI=1/C18H16N2O3/c1-12(14-5-3-2-4-6-14)20-18(23)15(11-19)9-13-7-8-16(21)17(22)10-13/h2-10,12,21-22H,1H3,(H,20,23)/b15-9+/t12-/m0/s1

Synonyms:

• Ag 835
• Alpha-Cyano-(+)-(S)-N-(Alpha-Phenethyl)-(3,4-Dihydroxy)Cinnamide
• (S)-(E)-2-Cyano-3-(3',4'-Dihydroxyphenyl)-N-(1-Phenylethyl)-2-Propenamide
• (+)-(S)-N-(Alpha-Methylbenzyl)-3,4-Dihydroxy-Benzylidenecyanoacetamide
• Tyrphostin B44, (+) Enantiomer
• Tyrphostin B50
• (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide
• (+)-Tyrphostin B44
• (+)-(s)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
• (+)-Enantiomer
• (S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide
• (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide
• (2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-[(1S)-1-Phenylethyl]-2-Propenamide
• Tyrphostin B50, (+)-(S)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
• Tyrphostin B44, (+) enantiomer AG835
• non-metastatic tumors,INBL,antitumor,(+)-Tyrphostin B44,Epidermal growth factor receptor,Tyrphostin B50,ErbB-1,Tyrphostin B-44, (+) enantiomer,Inhibitor,Tyrphostin B 50,CALO,cervical carcinoma cell,EGFR,inhibit,Tyrphostin B44, (+) enantiomer,Tyrphostin AG835,HER1,Tyrphostin AG-835,Tyrphostin AG 835,Tyrphostin B-50
• 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-, (2E)-

Tyrphostin AG 835

CAS: 133550-37-5

Formula: C₁₈H₁₆N₂O₃

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 308.34

Ref: 3B-T3540

(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-2-propenamide

CAS: 133550-37-5

Formula: C₁₈H₁₆N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 308.3312

Ref: IN-DA003988

Tyrphostin B44, (+) enantiomer

CAS: 133550-37-5

Tyrphostin B44, (+) enantiomer

Purity: ≥95%

Molecular weight: 308.33g/mol

Ref: 54-BUP08121

Tyrphostin AG 835

CAS: 133550-37-5

Formula: C₁₈H₁₆N₂O₃

Molecular weight: 308.33

Ref: 7W-GK7474

Tyrphostin B44, (+) enantiomer

CAS: 133550-37-5

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)

Formula: C₁₈H₁₆N₂O₃

Purity: 97.18%

Color and Shape: Solid

Molecular weight: 308.33

Ref: TM-T22450

(2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-[(1S)-1-Phenylethyl]-2-Propenamide

CAS: 133550-37-5

Purity: 97%

Molecular weight: 308.34

Ref: 10-F862487