Description:Boc-Lys(Fmoc)-OMe, also known as N-Boc-Nα-(9-fluorenylmethoxycarbonyl)-Lysine methyl ester, is a protected amino acid derivative commonly used in peptide synthesis. It features a lysine residue with two protective groups: the Boc (tert-butyloxycarbonyl) group, which protects the amino group, and the Fmoc (9-fluorenylmethoxycarbonyl) group, which protects the side chain amine. The methyl ester (OMe) provides protection for the carboxylic acid group, enhancing the compound's stability and solubility. This compound is typically utilized in solid-phase peptide synthesis, allowing for selective deprotection and coupling reactions. Its structure facilitates the formation of peptides with specific sequences while minimizing side reactions. The presence of the Boc and Fmoc groups allows for orthogonal protection strategies, making it versatile in synthetic chemistry. Additionally, Boc-Lys(Fmoc)-OMe is soluble in organic solvents, which is advantageous for various synthetic protocols. Overall, its protective groups and functional characteristics make it a valuable intermediate in the synthesis of complex peptides and proteins.
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