CymitQuimica logo

CAS 133645-46-2

:

3S)-Hydroxy Simvastatin

Description:
(3S)-Hydroxy Simvastatin, with the CAS number 133645-46-2, is a derivative of simvastatin, a widely used cholesterol-lowering medication. This compound is characterized by its structural features, which include a hydroxy group at the 3-position of the lactone ring, contributing to its pharmacological activity. It functions primarily as an HMG-CoA reductase inhibitor, which plays a crucial role in the biosynthesis of cholesterol in the liver. The presence of the hydroxy group enhances its solubility and bioavailability compared to its parent compound. (3S)-Hydroxy Simvastatin exhibits a high affinity for the target enzyme, leading to a significant reduction in low-density lipoprotein (LDL) cholesterol levels in the bloodstream. Additionally, it may possess antioxidant properties and contribute to cardiovascular health beyond its lipid-lowering effects. The compound is typically administered in oral form and is subject to metabolic processes in the liver, which can influence its efficacy and safety profile. As with other statins, potential side effects may include muscle pain, liver enzyme alterations, and gastrointestinal disturbances.
Formula:C25H38O6
InChI:InChI=1/C25H38O6/c1-6-25(4,5)24(29)31-21-10-14(2)9-16-11-20(27)15(3)19(23(16)21)8-7-18-12-17(26)13-22(28)30-18/h9,11,15,17-21,23,26-27H,6-8,10,12-13H2,1-5H3/t15-,17-,18-,19+,20?,21?,23+/m1/s1
Synonyms:
  • [1S-[1a,6a,7b,8b(2S*,4S*),8ab]]-1,2,6,7,8,8a-hexahydro-6-hydroxy-3,7-dimethyl)-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester 2,2-dimethyl-butanoic Aci
  • 2,2-Dimethylbutanoic Acid [1S-[1a,6a,7,8(2S*,4S*),8a]]-1,2,6,7,8,8a-Hexahydro-6-hydroxy-3,7-dimethyl)-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
  • (6S)-Hydroxy Simvastatin
    TLC
    + Info

    (6S)-Hydroxy Simvastatin

    CAS:
    Formula:C25H38O6
    Molecular weight:434.58

    Ref: 4Z-S-1221

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • 3’(S)-Hydroxy simvastatin
    Biosynth
    + Info

    3’(S)-Hydroxy simvastatin

    CAS:
    Please enquire for more information about 3’(S)-Hydroxy simvastatin including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Formula:C25H38O6
    Purity:Min. 95%
    Molecular weight:434.6 g/mol

    Ref: 3D-IFA64546

    2500µg
    1,577.00€