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CAS 133743-71-2

:

Watanidipine hydrochloride

Description:
Watanidipine hydrochloride is a pharmaceutical compound primarily classified as a calcium channel blocker, which is utilized in the management of hypertension and certain cardiovascular conditions. It functions by inhibiting the influx of calcium ions through L-type calcium channels in vascular smooth muscle and cardiac tissue, leading to vasodilation and reduced blood pressure. The compound is characterized by its hydrochloride salt form, which enhances its solubility and stability in aqueous solutions. Watanidipine exhibits a relatively selective action on vascular tissues, minimizing effects on cardiac contractility, which is beneficial for patients with specific cardiovascular profiles. Its pharmacokinetic properties include moderate absorption and a metabolism that may involve hepatic pathways. As with many medications, potential side effects can include dizziness, headache, and peripheral edema, among others. Due to its specific mechanism of action and therapeutic applications, Watanidipine hydrochloride is an important agent in the treatment of cardiovascular diseases, contributing to improved patient outcomes in managing blood pressure.
Formula:C41H42N4O6·2HCl
InChI:InChI=1/C41H42N4O6.2ClH/c1-28-36(40(46)50-3)38(33-15-10-16-35(27-33)45(48)49)37(29(2)42-28)41(47)51-26-21-30-17-19-34(20-18-30)43-22-24-44(25-23-43)39(31-11-6-4-7-12-31)32-13-8-5-9-14-32;;/h4-20,27,38-39,42H,21-26H2,1-3H3;2*1H
InChI key:InChIKey=MVMIPBPFTZGTBS-UHFFFAOYSA-N
SMILES:C(OCCC1=CC=C(C=C1)N2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)(=O)C=5C(C(C(OC)=O)=C(C)NC5C)C6=CC(N(=O)=O)=CC=C6.Cl
Synonyms:
  • AE 0047
  • CCRIS 7882
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl] 5-methyl ester, hydrochloride (1:2)
  • Watanidipine hydrochloride
  • 2-{4-[4-(diphenylmethyl)piperazin-1-yl]phenyl}ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride
  • Watanidipine HCl
  • Watanidipine dihydrochloride
  • Watanidipine hydrochloride
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(4-(4-(diphenylmethyl)-1-piperazinyl)phenyl)ethyl methyl ester, dihydrochloride
  • AE 0047
  • See more synonyms
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