CAS 133745-75-2

N-Fluorobenzenesulfonimide

Description:

N-Fluorobenzenesulfonimide (CAS 133745-75-2) is a fluorinating agent known for its utility in organic synthesis, particularly in the introduction of fluorine into various organic compounds. It is characterized by its stable structure, which consists of a sulfonamide group attached to a fluorine atom and a benzene ring. This compound is typically a white to off-white solid and is soluble in polar organic solvents. N-Fluorobenzenesulfonimide is recognized for its mild reactivity, allowing it to selectively fluorinate substrates without causing significant side reactions. It is often used in the synthesis of pharmaceuticals and agrochemicals, where the incorporation of fluorine can enhance biological activity and metabolic stability. Additionally, it is valued for its ease of handling and storage compared to other fluorinating agents. Safety precautions are necessary when working with this compound, as it can be hazardous if inhaled or ingested, and appropriate protective measures should be taken to mitigate exposure.

Formula: C₁₂H₁₀FNO₄S₂

InChI: InChI=1S/C12H10FNO4S2/c13-14(19(15,16)11-7-3-1-4-8-11)20(17,18)12-9-5-2-6-10-12/h1-10H

InChI key: InChIKey=RLKHFSNWQCZBDC-UHFFFAOYSA-N

SMILES: S(N(S(=O)(=O)C1=CC=CC=C1)F)(=O)(=O)C2=CC=CC=C2

Synonyms:

• 3,4-Bis(Trifluoromethyl)Benzoic Acid
• Accufluor NFSi
• Benzenesulfonamide, N-fluoro-N-(phenylsulfonyl)-
• Fluorobis(phenylsulfonyl)amine
• N-Fluoro-N-(benzenesulfonyl)benzenesulfonamide
• N-Fluoro-N-(phenylsulfonyl)benzenesulfonamide
• N-Fluorobenzene sulfonimide
• N-Fluorobenzenesulfonmide (NFSI)
• N-Fluorobenzenesulphonimide
• N-Fluorobis(phenylsulfonyl)amine
• N-Fluorodibenzenesulfonimide
• N-Phenylsulfonyl-N-fluorobenzenesulfonamide
• N-fluorobenzenesulfonamide
• Nfsi

N-Fluorobenzenesulfonimide [Fluorinating Reagent]

CAS: 133745-75-2

Formula: C₁₂H₁₀FNO₄S₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 315.33

Ref: 3B-F0335

N-Fluorobenzenesulfonimide, 97%

CAS: 133745-75-2

N-Fluorobenzenesulfonimide fluorinates aromatics, enolates, azaenolates and carbanions in high yield. It is used for diastereoselective fluorination of Li enolates of chiral carboximides, for directed fluorination of ortho-lithiated aromatics and for a review of electrophilic N-F fluorinating agents

Formula: C₁₂H₁₀FNO₄S₂

Purity: 97%

Color and Shape: White to cream to gray, Crystals or powder or crystalline powder or fused solid

Molecular weight: 315.33

Ref: 02-L13955

N-Fluorodibenzenesulfonimide

CAS: 133745-75-2

Formula: C₁₂H₁₀FNO₄S₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 315.3405

Ref: IN-DA0035DS

N-Fluorobenzenesulfonimide

CAS: 133745-75-2

Formula: C₁₂H₁₀FNO₄S₂

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 315.33

Ref: 10-F006185

N-Fluorobenzenesulfonimide

CAS: 133745-75-2

N-Fluorobenzenesulfonimide

Formula: C₁₂H₁₀FNO₄S₂

Purity: 98%

Color and Shape: white with brown particulates crystalline powder

Molecular weight: 315.34g/mol

Ref: 54-PC3487

N-Fluorobenzenesulfonimide

Controlled Product

CAS: 133745-75-2

Applications N-Fluorobenzenesulfonimide is a mild electrophilic fluorinating reagent

Formula: C₁₂H₁₀FNO₄S₂

Color and Shape: Neat

Molecular weight: 315.34

Ref: TR-F596833

N-Fluorobenzenesulfonimide

CAS: 133745-75-2

N-Fluorobenzenesulfonimide is an organic compound with the molecular formula CHFNS. It is a fluorinating agent that can be used for the synthesis of organic compounds. N-Fluorobenzenesulfonimide has been shown to have anti-inflammatory properties and has shown promising results in animal studies for the treatment of hepatitis. The mechanism of action is not fully understood, but it may involve the formation of hydrogen bonds between N-fluorobenzenesulfonimide and amino acid residues in proteins, leading to inhibition of protein synthesis.

Formula: C₁₂H₁₀FNO₄S₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 315.34 g/mol

Ref: 3D-FF37698