CAS 1337482-17-3

Sofosbuvir impurity F

CAS: 1337482-17-3

Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA

Formula: C₃₄H₄₅FN₄O₁₃P₂

Purity: 98.05%

Color and Shape: Solid

Molecular weight: 798.69

Ref: TM-T12961

Sofosbuvir impurity F

CAS: 1337482-17-3

Sofosbuvir impurity F

Purity: ≥98%

Molecular weight: 798.69g/mol

Ref: 54-BUP01476

Sofosbuvir Impurity 77

CAS: 1337482-17-3

Formula: C₃₄H₄₅FN₄O₁₃P₂

Molecular weight: 798.69

Ref: 4Z-S-055084

Sofosbuvir impurity F

CAS: 1337482-17-3

Purity: 98%

Molecular weight: 798.695

Ref: 10-F987676

Sofosbuvir 3',5'-Bis-(S)-phosphate

Controlled Product

CAS: 1337482-17-3

Applications Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)

Formula: C₃₄H₄₅FN₄O₁₃P₂

Color and Shape: Neat

Molecular weight: 798.686

Ref: TR-S675605

Sofosbuvir 3\',5\'-Bis-O-Phosphoramidate

CAS: 1337482-17-3

Formula: C₃₄H₄₅FN₄O₁₃P₂

Molecular weight: 798.69

Ref: ST-EA-CP-S45002