CAS 1337531-36-8: 7-Methyl-5-[1-[[3-(trifluoromethyl)phenyl]acetyl]-2,3-dihydro-1H-indol-5-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Description: 7-Methyl-5-[1-[[3-(trifluoromethyl)phenyl]acetyl]-2,3-dihydro-1H-indol-5-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups and heterocycles. The presence of a trifluoromethyl group indicates potential for significant lipophilicity and biological activity, often enhancing the compound's pharmacological properties. The indole and pyrrolopyrimidine moieties suggest potential interactions with biological targets, making it of interest in medicinal chemistry. This compound may exhibit properties such as anti-inflammatory or anticancer activities, typical of many indole derivatives. Its synthesis likely involves multi-step organic reactions, and it may be evaluated for its solubility, stability, and reactivity under various conditions. The CAS number 1337531-36-8 uniquely identifies this substance in chemical databases, facilitating research and regulatory considerations. Overall, the compound's structural complexity and functional diversity position it as a candidate for further investigation in drug development and therapeutic applications.

Formula: C₂₄H₂₀F₃N₅O

InChI: InChI=1S/C24H20F3N5O/c1-31-12-18(21-22(28)29-13-30-23(21)31)15-5-6-19-16(11-15)7-8-32(19)20(33)10-14-3-2-4-17(9-14)24(25,26)27/h2-6,9,11-13H,7-8,10H2,1H3,(H2,28,29,30)

InChI key: InChIKey=SIXVRXARNAVBTC-UHFFFAOYSA-N

SMILES: O=C(N1C=2C=CC(=CC2CC1)C3=CN(C=4N=CN=C(N)C43)C)CC5=CC=CC(=C5)C(F)(F)F

Synonyms:

• GSK 2606414
• 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
• 7-Methyl-5-[1-[[3-(trifluoromethyl)phenyl]acetyl]-2,3-dihydro-1H-indol-5-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
• Ethanone, 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]-

7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine

CAS: 1337531-36-8

• Formula: C₂₄H₂₀F₃N₅O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 451.4437

GSK2606414

CAS: 1337531-36-8

• Purity: 98.61%
• Molecular weight: 451.44g/mol

GSK2606414

CAS: 1337531-36-8

GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor.Cost-effective and quality-assured.

• Formula: C₂₄H₂₀F₃N₅O
• Purity: 100% - 98.63%
• Color and Shape: Solid
• Molecular weight: 451.44

GSK2606414

CAS: 1337531-36-8

GSK 2606414

CAS: 1337531-36-8

Inhibitor of EIF2AK3/PERK kinases

• Formula: C₂₄H₂₀F₃N₅O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 451.44 g/mol

GSK 2606414-d3

CAS: 1337531-36-8

• Formula: C₂₄D₃H₁₉F₃N₅O
• Color and Shape: Neat
• Molecular weight: 456.478

GSK 2606414

CAS: 1337531-36-8

Applications GSK 2606414 acts as a potent and selective inhibitor of protein kinase R and …

• Formula: C₂₄H₂₀F₃N₅O
• Color and Shape: Neat
• Molecular weight: 451.44