CAS 1338055-88-1

Colistin B Sulfate Salt (~90%)

Description:

Colistin B sulfate salt is an antibiotic substance derived from the bacterium *Bacillus polymyxa*. It belongs to the polymyxin class of antibiotics, which are primarily effective against Gram-negative bacteria. Colistin B is known for its ability to disrupt bacterial cell membranes, leading to cell death, making it a valuable treatment option for multidrug-resistant infections. The sulfate salt form enhances its solubility in aqueous solutions, facilitating its use in clinical settings. Colistin B sulfate is typically administered via intravenous or inhalation routes, especially in severe infections caused by resistant strains such as *Pseudomonas aeruginosa*. Its use, however, is often limited by potential nephrotoxicity and neurotoxicity, necessitating careful monitoring of renal function during treatment. Additionally, the emergence of colistin resistance among bacteria poses a significant challenge in antibiotic therapy. Overall, while Colistin B sulfate remains a critical option in the antibiotic arsenal, its application must be judiciously managed to mitigate adverse effects and resistance development.

Formula: C₅₂H₁₀₀N₁₆O₁₇S

Synonyms:

• Colistin B Sulfate Salt (~90%)

Colistin B Pentatrifluoroacetate (Polymyxin E2 Pentatrifluoroacetate)

CAS: 1338055-88-1, 7239-48-7

Formula: C₅₂H₉₈N₁₆O₁₃·5C₂HF₃O₂

Molecular weight: 1155.46 5*114.02

Ref: 4Z-PC-321003

Polymyxin E2 sulfate

CAS: 1338055-88-1

Polymyxin E2, a key component of the cationic lipopeptide antibiotic colistin, was originally derived from B.

Formula: C₅₂H₉₈N₁₆O₁₃·XH₂SO₄

Color and Shape: Solid

Molecular weight: 1155.40

Ref: TM-T83904

Colistin B Sulfate Salt (~90%)

CAS: 1338055-88-1

Applications Colistin B Sulfate Salt is sulfate salt form of Colistin B which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.
References Naghmouchi, K. et al.: Arch. Microbio. 194, 363 (2012); Spapen, H. et al.: Annal. Int. Care, 1, 14 (2011);

Formula: C₅₂H₉₈N₁₆O₁₃·H₂O₄S

Purity: ~90%

Color and Shape: White

Molecular weight: 1253.51

Ref: TR-C641515

Colistin B Sulfate

CAS: 1338055-88-1

Formula: C₅₂H₉₈N₁₆O₁₃H₂SO₄

Molecular weight: 1155.46 :98.07

Ref: ST-EA-CP-C116011