CAS 133841-14-2

1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-7-(phenylmethoxy)-, endo-

Description:

1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-7-(phenylmethoxy)-, endo- is a complex organic compound characterized by its indazole core, which is a five-membered aromatic ring containing two nitrogen atoms. The presence of a carboxamide functional group indicates potential for hydrogen bonding and solubility in polar solvents. The compound features a bicyclic structure, which contributes to its three-dimensional conformation and may influence its biological activity. The methyl and phenylmethoxy substituents enhance its lipophilicity, potentially affecting its pharmacokinetic properties. This compound may exhibit specific interactions with biological targets, making it of interest in medicinal chemistry. Its unique structural features suggest potential applications in drug development, particularly in areas requiring modulation of biological pathways. As with many organic compounds, its stability, reactivity, and solubility will depend on environmental conditions such as pH and temperature. Further studies would be necessary to fully elucidate its properties and potential applications.

Formula: C₂₅H₃₀N₄O₂

InChI: InChI=1/C25H30N4O2/c1-28-19-10-6-11-20(28)15-18(14-19)26-25(30)23-21-12-7-13-22(24(21)29(2)27-23)31-16-17-8-4-3-5-9-17/h3-5,7-9,12-13,18-20H,6,10-11,14-16H2,1-2H3,(H,26,30)/t18-,19+,20-

InChI key: InChIKey=VZSXQQMZYQDDQE-ACDBMABINA-N

SMILES: C(N[C@H]1C[C@@]2(N(C)[C@](C1)(CCC2)[H])[H])(=O)C=3C=4C(=C(OCC5=CC=CC=C5)C=CC4)N(C)N3

Synonyms:

• 9-Azabicyclo[3.3.1]nonane, 1H-indazole-3-carboxamide deriv.
• 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-7-(phenylmethoxy)-, endo-

7-Benzyloxy Granisetron

Controlled Product

CAS: 133841-14-2

Applications 7-Benzyloxy Granisetron is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.
References Bloomer, J., et al.: Brit. J. Clin. Pharmacol., 38, 557 (1994); Vernekar, S.,e t al.: J. Med. Chem., 53, 2324 (2010); Kilpatrick, G.J., et al.: Nature, 330, 746 (1987); Durig, T., et al.: J. Pharm. Sci., 86, 1092 (1997); Yuasa, H., et al.: Chem. Pharm. Bull., 44, 1361 (1996)

Formula: C₂₅H₃₀N₄O₂

Color and Shape: Neat

Molecular weight: 418.53

Ref: TR-B286820

7-Benzyloxy granisetron

Controlled Product

CAS: 133841-14-2

Please enquire for more information about 7-Benzyloxy granisetron including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₅H₃₀N₄O₂

Purity: Min. 95%

Molecular weight: 418.5 g/mol

Ref: 3D-IFA84114