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CAS 133841-15-3

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7-Hydroxygranisetron

Description:
7-Hydroxygranisetron is a chemical compound that is a derivative of granisetron, which is primarily known for its use as an antiemetic agent to prevent nausea and vomiting, particularly in patients undergoing chemotherapy. This compound features a hydroxyl group (-OH) at the 7-position of the granisetron structure, which may influence its pharmacological properties and interactions. It is characterized by its molecular formula, which reflects the presence of carbon, hydrogen, nitrogen, and oxygen atoms. The compound exhibits a specific stereochemistry, which is crucial for its biological activity. As a metabolite of granisetron, 7-hydroxygranisetron may contribute to the overall therapeutic effects and side effects associated with granisetron treatment. Its solubility, stability, and interaction with biological targets are important factors in its pharmacokinetics and pharmacodynamics. Research into this compound may provide insights into its potential applications in clinical settings and its role in the metabolism of granisetron.
Formula:C18H24N4O2
Synonyms:
  • 7-Hydroxy Granisetron
  • 7-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
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