CAS 1338466-77-5

7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Description:

The chemical substance with the name "7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine" and CAS number "1338466-77-5" is a complex organic compound characterized by its unique structural features, including a pyrrolo[2,3-d]pyrimidine core and multiple functional groups. This compound likely exhibits properties typical of nucleoside analogs, which may include interactions with biological macromolecules such as DNA or RNA. Its structure suggests potential applications in medicinal chemistry, particularly in the development of therapeutic agents targeting specific biological pathways. The presence of various substituents, such as the tert-butyl group and amino functionalities, may influence its solubility, stability, and biological activity. Additionally, the compound's stereochemistry and the presence of a ribofuranosyl moiety could affect its pharmacokinetic properties. Overall, this substance represents a class of compounds that may hold promise for further research in drug development and biochemistry.

Formula: C₂₈H₄₁N₇O₄

InChI: InChI=1S/C28H41N7O4/c1-17(2)34(13-6-12-30-27(38)33-19-9-7-18(8-10-19)28(3,4)5)15-21-22(36)23(37)26(39-21)35-14-11-20-24(29)31-16-32-25(20)35/h7-11,14,16-17,21-23,26,36-37H,6,12-13,15H2,1-5H3,(H2,29,31,32)(H2,30,33,38)/t21-,22-,23-,26-/m1/s1

InChI key: InChIKey=WXRGFPHDRFQODR-ICLZECGLSA-N

SMILES: O[C@H]1[C@H](N2C=3C(C=C2)=C(N)N=CN3)O[C@H](CN(CCCNC(NC4=CC=C(C(C)(C)C)C=C4)=O)C(C)C)[C@H]1O

Synonyms:

• 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• EPZ 004777
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-
• EPZ004777
• 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 1-(3-((((2R,3S,4R,5R)-5-(4-AMino-7H-pyrrolo[2,3-d]pyriMidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl)(isopropyl)aMino)propyl)-3-(4-(tert-butyl)phenyl)urea
• 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine EPZ 004777

EPZ004777

CAS: 1338466-77-5

Formula: C₂₈H₄₁N₇O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 539.6696

Ref: IN-DA009CBC

EPZ004777

CAS: 1338466-77-5

EPZ004777

Purity: ≥98%

Molecular weight: 539.67g/mol

Ref: 54-BUP08099

EPZ004777

CAS: 1338466-77-5

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

Formula: C₂₈H₄₁N₇O₄

Purity: 98.99% - 99.32%

Color and Shape: Solid

Molecular weight: 539.67

Ref: TM-T3081

EPZ 004777

Controlled Product

CAS: 1338466-77-5

Formula: C₂₈H₄₁N₇O₄

Color and Shape: Neat

Molecular weight: 539.67

Ref: TR-E592055

EPZ 004777

CAS: 1338466-77-5

Highly potent DOT1L inhibitor

Formula: C₂₈H₄₁N₇O₄

Purity: Min. 95%

Molecular weight: 539.67 g/mol

Ref: 3D-BE162783