CAS: 1338466-77-5 - 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Formula: C₂₈H₄₁N₇O₄

InChI: InChI=1S/C28H41N7O4/c1-17(2)34(13-6-12-30-27(38)33-19-9-7-18(8-10-19)28(3,4)5)15-21-22(36)23(37)26(39-21)35-14-11-20-24(29)31-16-32-25(20)35/h7-11,14,16-17,21-23,26,36-37H,6,12-13,15H2,1-5H3,(H2,29,31,32)(H2,30,33,38)/t21-,22-,23-,26-/m1/s1

InChI key: InChIKey=WXRGFPHDRFQODR-ICLZECGLSA-N

SMILES: O=C(NC1=CC=C(C=C1)C(C)(C)C)NCCCN(CC2OC(N3C=CC=4C(=NC=NC43)N)C(O)C2O)C(C)C

Synonyms:

• 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• EPZ 004777
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-

EPZ004777

CAS: 1338466-77-5

• Formula: C₂₈H₄₁N₇O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 539.6696

EPZ004777

CAS: 1338466-77-5

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

• Formula: C₂₈H₄₁N₇O₄
• Purity: 98.99% - 99.32%
• Color and Shape: Solid
• Molecular weight: 539.67

EPZ 004777

CAS: 1338466-77-5

• Formula: C₂₈H₄₁N₇O₄
• Color and Shape: Neat
• Molecular weight: 539.67

EPZ 004777

CAS: 1338466-77-5

Highly potent DOT1L inhibitor

• Formula: C₂₈H₄₁N₇O₄
• Purity: Min. 95%
• Molecular weight: 539.67 g/mol