CAS 1338466-77-5: 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Description: The chemical substance with the name "7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine" and CAS number "1338466-77-5" is a complex organic compound characterized by its unique structural features, including a pyrrolo[2,3-d]pyrimidine core and multiple functional groups. This compound likely exhibits properties typical of nucleoside analogs, which may include interactions with biological macromolecules such as DNA or RNA. Its structure suggests potential applications in medicinal chemistry, particularly in the development of therapeutic agents targeting specific biological pathways. The presence of various substituents, such as the tert-butyl group and amino functionalities, may influence its solubility, stability, and biological activity. Additionally, the compound's stereochemistry and the presence of a ribofuranosyl moiety could affect its pharmacokinetic properties. Overall, this substance represents a class of compounds that may hold promise for further research in drug development and biochemistry.

Formula: C₂₈H₄₁N₇O₄

InChI: InChI=1S/C28H41N7O4/c1-17(2)34(13-6-12-30-27(38)33-19-9-7-18(8-10-19)28(3,4)5)15-21-22(36)23(37)26(39-21)35-14-11-20-24(29)31-16-32-25(20)35/h7-11,14,16-17,21-23,26,36-37H,6,12-13,15H2,1-5H3,(H2,29,31,32)(H2,30,33,38)/t21-,22-,23-,26-/m1/s1

InChI key: InChIKey=WXRGFPHDRFQODR-ICLZECGLSA-N

SMILES: O=C(NC1=CC=C(C=C1)C(C)(C)C)NCCCN(CC2OC(N3C=CC=4C(=NC=NC43)N)C(O)C2O)C(C)C

Synonyms:

• 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• EPZ 004777
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-

EPZ004777

CAS: 1338466-77-5

• Formula: C₂₈H₄₁N₇O₄
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 539.6696

EPZ004777

CAS: 1338466-77-5

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

• Formula: C₂₈H₄₁N₇O₄
• Purity: 98.99% - 99.32%
• Color and Shape: Solid
• Molecular weight: 539.67

EPZ 004777

CAS: 1338466-77-5

• Formula: C₂₈H₄₁N₇O₄
• Color and Shape: Neat
• Molecular weight: 539.67

EPZ 004777

CAS: 1338466-77-5

Highly potent DOT1L inhibitor

• Formula: C₂₈H₄₁N₇O₄
• Purity: Min. 95%
• Molecular weight: 539.67 g/mol