CAS 133865-89-1

Safinamide

Description:

Safinamide is a pharmaceutical compound primarily used in the treatment of Parkinson's disease. It functions as both a monoamine oxidase inhibitor and a glutamate release modulator, which contributes to its therapeutic effects. The chemical structure of safinamide includes a phenyl group and a sulfonamide moiety, which are integral to its activity. It is typically administered orally and is known for its ability to enhance dopaminergic activity in the brain, thereby alleviating motor symptoms associated with Parkinson's disease. Safinamide is characterized by its moderate solubility in water and its stability under standard storage conditions. The compound has a favorable pharmacokinetic profile, with a relatively long half-life, allowing for once-daily dosing. Additionally, safinamide has been shown to have neuroprotective properties, making it a valuable option in the management of Parkinson's disease, particularly in patients experiencing fluctuations in their symptoms. As with any medication, potential side effects and contraindications should be considered, and it is essential for patients to consult healthcare professionals for personalized advice.

Formula: C₁₇H₁₉FN₂O₂

InChI: InChI=1S/C17H19FN2O2/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14/h2-9,12,20H,10-11H2,1H3,(H2,19,21)/t12-/m0/s1

InChI key: InChIKey=NEMGRZFTLSKBAP-LBPRGKRZSA-N

SMILES: O(CC1=CC(F)=CC=C1)C2=CC=C(CN[C@H](C(N)=O)C)C=C2

Synonyms:

• (2S)-2-[[4-[(3-Fluorophenyl)methoxy]phenyl]methylamino]propanamide
• (2S)-2-[[[4-[(3-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide
• (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide
• (S)-2-[[[4-[(3-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide
• Emd 1195686
• Fce 26743
• N~2~-{4-[(3-fluorobenzyl)oxy]benzyl}-L-alaninamide
• Propanamide, 2-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-, (2S)-
• Propanamide, 2-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-, (S)-
• Safinamide

(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide

CAS: 133865-89-1

Formula: C₁₇H₁₉FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 302.3434

Ref: IN-DA0038Y6

Safinamide

CAS: 133865-89-1

Safinamide

Purity: ≥98%

Molecular weight: 302.34g/mol

Ref: 54-BUP16818

(S)-2-((4-((3-Fluorobenzyl)Oxy)Benzyl)Amino)Propanamide

CAS: 133865-89-1

(S)-2-((4-((3-Fluorobenzyl)Oxy)Benzyl)Amino)Propanamide

Purity: 98%

Molecular weight: 302.34g/mol

Ref: 54-PC109253

Safinamide

CAS: 133865-89-1

Formula: C₁₇H₁₉FN₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 302.35

Ref: 4Z-S-073001

Safinamide

CAS: 133865-89-1

Safinamide: reversible MAO-B inhibitor, enhances dopamine, blocks glutamate release, sodium, calcium channels; may treat Parkinson's, RLS, epilepsy.

Formula: C₁₇H₁₉FN₂O₂

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 302.34

Ref: TM-T6651L

Safinamide

CAS: 133865-89-1

Formula: C₁₇H₁₉FN₂O₂

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 302.35

Ref: 3B-S0935

(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide

CAS: 133865-89-1

Formula: C₁₇H₁₉FN₂O₂

Purity: 95.0%

Molecular weight: 302.349

Ref: 10-F222585