Description:Valnemulin hydrochloride is a synthetic antibiotic belonging to the pleuromutilin class, primarily used in veterinary medicine for the treatment of bacterial infections in livestock, particularly in pigs. It exhibits broad-spectrum antimicrobial activity against various Gram-positive bacteria and some Gram-negative strains. The compound functions by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit, which disrupts the translation process essential for bacterial growth and reproduction. Valnemulin is typically administered orally or via injection, and its pharmacokinetics indicate good absorption and distribution in animal tissues. The hydrochloride salt form enhances its solubility and stability. Safety and efficacy studies have established its use in veterinary applications, although it is important to adhere to withdrawal periods before animal products are consumed to avoid antibiotic residues. As with any antibiotic, the potential for resistance development necessitates careful management of its use in agricultural settings.
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