CAS 133868-46-9
:VALNEMULIN HYDROCHLORIDE
Description:
Valnemulin hydrochloride is a synthetic antibiotic belonging to the pleuromutilin class, primarily used in veterinary medicine for the treatment of bacterial infections in livestock, particularly in pigs. It exhibits broad-spectrum antimicrobial activity against various Gram-positive bacteria and some Gram-negative strains. The compound functions by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit, which disrupts the translation process essential for bacterial growth and reproduction. Valnemulin is typically administered orally or via injection, and its pharmacokinetics indicate good absorption and distribution in animal tissues. The hydrochloride salt form enhances its solubility and stability. Safety and efficacy studies have established its use in veterinary applications, although it is important to adhere to withdrawal periods before animal products are consumed to avoid antibiotic residues. As with any antibiotic, the potential for resistance development necessitates careful management of its use in agricultural settings.
Formula:C31H53ClN2O5S
InChI:InChI=1S/C31H52N2O5S.ClH/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31;/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37);1H/t19-,20+,22-,24-,25+,26+,29-,30+,31+;/m1./s1
InChI key:MFBPRQKHDIVLOJ-AFFLPQGKSA-N
SMILES:C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CSC(C)(C)CNC(=O)[C@@H](C(C)C)N)C.Cl
Synonyms:- Econor
- Valnemulin HCL
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Valnemulin Hydrochloride
CAS:Formula:C31H52N2O5S·HClPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:601.28VALNEMULIN HYDROCHLORIDE CRS
CAS:VALNEMULIN HYDROCHLORIDE CRSFormula:C31H53ClN2O5SMolecular weight:601.2809Valnemulin Hydrochloride
CAS:Valnemulin HydrochlorideFormula:C31H53ClN2O5SPurity:>98%Molecular weight:601.28Valnemulin hydrochloride
CAS:Valnemulin hydrochlorideFormula:C31H52N2O5S·HClPurity:≥98%Molecular weight:601.28Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, hydrochloride (1:1)
CAS:Formula:C31H53ClN2O5SPurity:98.0%Color and Shape:SolidMolecular weight:601.2809Valnemulin hydrochloride
CAS:Controlled ProductFormula:C31H52N2O5S·ClHColor and Shape:NeatMolecular weight:601.28Valnemulin Hydrochloride
CAS:Applications Valnemulin Hydrochloride is a semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial.
References Horkovics-Kovats, S., et al.: J. Pharm. Med., 6, 149 (1996); Jordan, F.T.W., et al.: Avian Dis., 42, 738 (1998); Aitken, I.A., et al.: Vet. Rec., 144, 128 (1999); Poulsen, S.M., et al.: Mol. Microbiol., 41, 1091 (2001);Formula:C31H52N2O5S·ClHColor and Shape:NeatMolecular weight:601.28Valnemulin hydrochloride
CAS:Valnemulin hydrochloride (Valnemulin HCl), a broad-spectrum bacteriostatic agent, inhibits protein synthesis in bacteria by binding to the peptidyl transferase.Formula:C31H53ClN2O5SPurity:99.64% - 99.74%Color and Shape:White SolidMolecular weight:601.281Valnemulin Hydrocloride
CAS:Valnemulin Hydrochloride is a fatty acid that is used as an antimicrobial agent. It has been shown to have anti-cancer effects in some animal models. Valnemulin hydrochloride inhibits the growth of bacteria, fungi, and viruses. It is not active against bacterial spores and mycobacteria. Valnemulin hydrochloride binds to the bacterial cell membrane and causes increased permeability, leading to cell death. The bioavailability of valnemulin hydrochloride is low due to its high lipophilicity, which can be improved by complexation with sodium citrate or sodium carbonate. This drug has been tested in vitro against a number of human infectious diseases such as chlamydia trachomatis, staphylococcus epidermidis, pseudomonas aeruginosa, streptococcus pyogenes, and herpes simplex virus type 1 (HSV-1). Valnemulin hydrochloride also showsFormula:C31H52N2O5S·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:601.28 g/mol
![Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,…](https://static.cymitquimica.com/products/IN/thumb/DA009B8H.jpg)
