CAS 13389-03-2
:8-BROMO-2'-DEOXYGUANOSINE
Description:
8-Bromo-2'-deoxyguanosine is a modified nucleoside that serves as an important tool in molecular biology and biochemistry. It is a derivative of deoxyguanosine, where a bromine atom is substituted at the 8-position of the purine ring. This modification can influence the nucleoside's base-pairing properties and its incorporation into DNA, making it useful for studying DNA replication and repair mechanisms. The presence of the bromine atom can also enhance the compound's reactivity, allowing it to participate in various chemical reactions, including those involved in the formation of DNA adducts. 8-Bromo-2'-deoxyguanosine is often used in research to investigate the effects of oxidative stress and the role of modified nucleotides in mutagenesis. Its CAS number, 13389-03-2, is a unique identifier that facilitates the cataloging and retrieval of information related to this compound in chemical databases. Overall, this nucleoside plays a significant role in understanding the biochemical pathways and interactions within cellular systems.
Formula:C10H12BrN5O4
InChI:InChI=1/C10H12BrN5O4/c11-9-13-6-7(14-10(12)15-8(6)19)16(9)5-1-3(18)4(2-17)20-5/h3-5,17-18H,1-2H2,(H3,12,14,15,19)
InChI key:InChIKey=MKDXZFVCXWXGBQ-VPENINKCSA-N
SMILES:BrC=1N(C2=C(N1)C(=O)N=C(N)N2)[C@@H]3O[C@H](CO)[C@@H](O)C3
Synonyms:- 2-amino-8-bromo-9-(2-deoxypentofuranosyl)-3,9-dihydro-6H-purin-6-one
- 8-Bromo-2'-deoxy-D-guanosine
- Guanosine, 8-bromo-2′-deoxy-
- NSC 105830
- 8-Bromo-2′-deoxyguanosine
- 2-Amino-8-bromo-9-((2R,4S,5R)
- 8-Br-2'-dG
- 8-Br-dG
- 2'-Deoxy-8-bromoguanosine
- -4-hydroxy-5-(hydroxymethyl)
- 2-AMino-8-broMo-9-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 9 products.
8-Bromo-2'-deoxyguanosine, 99%
CAS:<p>8-Bromo-2'-deoxyguanosine is useful as the starting structure for 2'-deoxyguanosine nucleotides, which are modified in position 8. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy </p>Formula:C10H12BrN5O4Purity:99%Color and Shape:PowderMolecular weight:346.14Guanosine, 8-bromo-2'-deoxy-
CAS:Formula:C10H12BrN5O4Purity:98%Color and Shape:SolidMolecular weight:346.13742-Amino-8-Bromo-9-((2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-1H-Purin-6(9H)-One
CAS:<p>2-Amino-8-Bromo-9-((2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-1H-Purin-6(9H)-One</p>Purity:98%Molecular weight:346.14g/mol8-Bromo-2'-deoxyguanosine
CAS:<p>8-Bromo-2'-deoxyguanosine is a 2'-Deoxynucleoside; Halo-nucleoside.</p>Formula:C10H12BrN5O4Color and Shape:SolidMolecular weight:346.148-Bromo-2’-deoxyguanosine
CAS:Controlled Product<p>Applications 8-Bromo-2’-deoxyguanosine (cas# 13389-03-2) is a compound useful in organic synthesis.<br>References Chatgilialoglu, C., et al.: Chem. Res. Toxicol., 20, 1820 (2007),<br></p>Formula:C10H12BrN5O4Color and Shape:NeatMolecular weight:346.148-Bromo-2'-deoxyguanosine
CAS:<p>8-Bromo-2'-deoxyguanosine is a reactive brominated compound that has been shown to stabilize DNA strands. The effects of 8-bromo-2'-deoxyguanosine on the stability of DNA are due to the steric interactions between the bromine and amines in the DNA backbone, which prevent nucleophilic attack. 8-Bromo-2'-deoxyguanosine is an antihistamine, but it has also been used as a precursor for other drugs such as zidovudine, an antiviral drug used in HIV/AIDS therapy. It has also been proposed as a potential treatment for atherosclerosis.</p>Formula:C10H12BrN5O4Purity:Min. 90 Area-%Color and Shape:Off-White PowderMolecular weight:346.14 g/mol8-Bromo-2’-deoxyguanosine-13C,15N2 (>90%)
CAS:Controlled Product<p>Applications 8-Benzyloxy-2’-deoxyguanosine-13C,15N2 is a compound useful in organic synthesis.<br></p>Formula:CC9H12Br15N2N3O4Color and Shape:NeatMolecular weight:349.117
